Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2859509 | 0.91 | KMT2A (0.54) | ALDH1A1MAPTSMN1; SMN2NOTUMEPHX1 | |
| SCHEMBL2853344 | 0.89 | HPGD (0.55) | ALDH1A1MAPTCCR1SMN1; SMN2TP53 | |
| SCHEMBL2852238 | 0.89 | GAA (0.55) | GAASMN1; SMN2TP53KDM4EEPHX1 | |
| SCHEMBL2863134 | 0.88 | CCR1 (0.48) | ALDH1A1MAPTCCR1SMN1; SMN2NPSR1 | |
| SCHEMBL2853267 | 0.85 | HPGD (0.55) | ALDH1A1MAPTCCR1SMN1; SMN2TP53 | |
| SCHEMBL2857180 | 0.83 | NPSR1 (0.53) | MAPTGAACCR1TP53POLB | |
| SCHEMBL2854802 | 0.82 | LMNA (0.48) | ALDH1A1MAPTGAACCR1TP53 | |
| SCHEMBL2861261 | 0.81 | HPGD (0.64) | ALDH1A1MAPTGAASMN1; SMN2KMT2A | |
| SCHEMBL2854625 | 0.81 | POLB (0.48) | ALDH1A1GAACCR1TP53TDP1 | |
| SCHEMBL2857468 | 0.80 | MAPT (0.47) | ALDH1A1MAPTCCR1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |