Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.48 |
| ▸ | SMO | Q99835 | 7/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857180 | 0.94 | NPSR1 (0.53) | CCR1SMOMAPK1P2RX7NPSR1 | |
| SCHEMBL2853344 | 0.94 | HPGD (0.55) | CCR1SMOMAPK1P2RX7HPGD | |
| SCHEMBL2853267 | 0.94 | HPGD (0.55) | CCR1SMOMAPK1P2RX7FAAH | |
| SCHEMBL2854802 | 0.94 | LMNA (0.48) | CCR1FAAHALDH1A1RORCMAPT | |
| SCHEMBL2857468 | 0.88 | MAPT (0.47) | CCR1SMOP2RX7HPGDNPSR1 | |
| SCHEMBL2856499 | 0.88 | ALDH1A1 (0.53) | CCR1HPGDNPSR1ALDH1A1MAPT | |
| SCHEMBL2851002 | 0.86 | SMN1; SMN2 (0.53) | SMOMAPK1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL2854625 | 0.85 | POLB (0.48) | CCR1P2RX7HPGDALDH1A1 | |
| SCHEMBL2861261 | 0.85 | HPGD (0.64) | MAPK1HPGDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2850369 | 0.84 | P2RX7 (0.56) | CCR1P2RX7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |