Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 3/20 | 0.48 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 11/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1933457 | 0.90 | ZDHHC20 (0.39) | ZDHHC20ZDHHC2TSHRACHE | |
| SCHEMBL15260550 | 0.90 | ZDHHC20 (0.44) | ZDHHC20ZDHHC2TSHREPHX1FAAH | |
| SCHEMBL10945908 | 0.89 | ZDHHC20 (0.39) | ZDHHC20ZDHHC2TSHRACHE | |
| Methacrylic Acid SCHEMBL7795521 | 0.89 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2TSHREPHX1FAAH | |
| SCHEMBL1563110 | 0.88 | ZDHHC20 (0.46) | ZDHHC20ZDHHC2TSHREPHX1FAAH | |
| Methacrylic Acid SCHEMBL27993332 | 0.84 | ZDHHC20 (0.41) | ZDHHC20ZDHHC2TSHRTGM2 | |
| SCHEMBL7713603 | 0.82 | ZDHHC20 (0.37) | ZDHHC20ZDHHC2TSHR | |
| SCHEMBL7745652 | 0.82 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2TSHRACHEEPHX1 | |
| Acrylic Acid SCHEMBL21239504 | 0.82 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2TSHRACHETGM2 | |
| SCHEMBL31036566 | 0.81 | ZDHHC20 (0.73) | ZDHHC20ZDHHC2TSHREPHX1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200190052-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND COMPOSITIONS COMPRISING SUCH ACTIVE INGREDIENTS | BASF SE (DE) | 2020-06-18 | — | — | US | disclosed |
| US-10584134-B2 | Use of physiological cooling active ingredients, and agents containing such active ingredients | SYMRISE AG (DE) | 2020-03-10 | — | — | US | disclosed |
| US-20180093997-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | SYMRISE AG (DE) | 2018-04-05 | — | — | US | disclosed |
| US-9718839-B2 | Use of physiological cooling active ingredients, and agents containing such active ingredients | SYMRISE AG (DE) | 2017-08-01 | — | — | US | disclosed |
| US-20150086491-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | SYMRISE AG (DE) | 2015-03-26 | — | — | US | disclosed |
| US-8927605-B2 | Use of physiological cooling active ingredients, and agents containing such active ingredients | SYMRISE AG (DE) | 2015-01-06 | — | — | US | disclosed |
| US-8765688-B2 | Anti-dandruff compositions containing peptides | BASF SE (DE) | 2014-07-01 | — | — | US | disclosed |
| US-20130085186-A1 | COSMETIC PREPARATIONS BASED ON MOLECULARLY IMPRINTED POLYMERS | BASF SE (DE) | 2013-04-04 | — | — | US | disclosed |
| US-20120263659-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | BASF SE (DE) | 2012-10-18 | — | — | US | disclosed |
| US-20100310644-A1 | ANTI-DANDRUFF COMPOSITIONS CONTAINING PEPTIDES | BASF ,Trademarks and Licenses (DE) | 2010-12-09 | — | — | US | disclosed |
| US-20100048737-A1 | COSMETIC PREPARATIONS BASED ON MOLECULARLY IMPRINTED POLYMERS | BASF SE (DE) | 2010-02-25 | — | — | US | disclosed |
| WO-2010010145-A1 | KERATIN-BINDING POLYPEPTIDES AND METHOD FOR THEIR IDENTIFICATION | BASF SE (DE) | 2010-01-28 | — | — | WO | disclosed |
| US-20100015070-A1 | USE OF NATURAL, RECOMBINANT AND SYNTHETIC RESILINS IN COSMETICS | BASF SE (DE) | 2010-01-21 | — | — | US | disclosed |
| WO-2009080306-A1 | ANTI-DANDRUFF COMPOSITIONS CONTAINING PEPTIDES | BASF SE (DE) | 2009-07-02 | — | — | WO | disclosed |
| US-20090156485-A1 | METHOD FOR COUPLING KERATIN-BINDING POLYPEPTIDES WITH EFFECTOR MOLECULES WHICH SUPPORT CARBOXYLIC GROUPS OR SULFONIC ACID GROUPS | BASE SE (DE) | 2009-06-18 | — | — | US | disclosed |
| US-20090136433-A1 | Use of Hydrophobin-Polypeptides and Conjugates From Hydrophobin-Polypeptides Having Active and Effect Agents and the Production Thereof and Use Thereof In the Cosmetic Industry | BASF AKTIENGESELLSCHAFT (DE) | 2009-05-28 | — | — | US | disclosed |
| US-20090099075-A1 | Chimeric Keratin-Binding Effector Proteins | BASF SE (DE) | 2009-04-16 | — | — | US | disclosed |
| US-20090098076-A1 | Method For the Production of a Keratin-Binding Effector Molecule | BASF SE (DE) | 2009-04-16 | — | — | US | disclosed |
| US-20080220031-A1 | Dermocosmetic Preparations | BASF AKTIENGESELLSCHAFT (DE) | 2008-09-11 | — | — | US | disclosed |
| US-20080075684-A1 | Keratin-Binding Polypeptides | BASF AKTIENGESELLSCHAFT (DE) | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130085186-A1 | COSMETIC PREPARATIONS BASED ON MOLECULARLY IMPRINTED POLYMERS | PRDM7, FABP4, PLIN1 | ZDHHC20 525/4885ZDHHC2 789/4885TSHR 4219/4885 |
| US-20090156485-A1 | METHOD FOR COUPLING KERATIN-BINDING POLYPEPTIDES WITH EFFECTOR MOLECULES WHICH SUPPORT CARBOXYLIC GROUPS OR SULFONIC ACID GROUPS | KRT18, KRTCAP2, CUTA | ZDHHC20 1217/4885ZDHHC2 1584/4885TSHR 2645/4885 |
| US-20090136433-A1 | Use of Hydrophobin-Polypeptides and Conjugates From Hydrophobin-Polypeptides Having Active and Effect Agents and the Production Thereof and Use Thereof In the Cosmetic Industry | KRT18, F12, XPA | ZDHHC20 742/4885ZDHHC2 2052/4885TSHR 2541/4885 |
| US-20100048737-A1 | COSMETIC PREPARATIONS BASED ON MOLECULARLY IMPRINTED POLYMERS | PRDM7, FABP4, PLIN1 | ZDHHC20 525/4885ZDHHC2 789/4885TSHR 4219/4885 |
| US-20150086491-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | TRPM8, TRPM7, TRPM2 | ZDHHC20 2278/4885ZDHHC2 3318/4885TSHR 2364/4885 |
| US-20080220031-A1 | Dermocosmetic Preparations | C3AR1, C1S, C1R | ZDHHC20 293/4885ZDHHC2 329/4885TSHR 3133/4885 |
| US-10584134-B2 | Use of physiological cooling active ingredients, and agents containing such active ingredients | TRPM8, TRPM7, TRPM2 | ZDHHC20 2278/4885ZDHHC2 3318/4885TSHR 2364/4885 |
| US-20180093997-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | TRPM8, TRPM7, TRPM2 | ZDHHC20 2278/4885ZDHHC2 3318/4885TSHR 2364/4885 |
| US-20090099075-A1 | Chimeric Keratin-Binding Effector Proteins | KRT18, KRTCAP2, CKAP4 | ZDHHC20 1142/4885ZDHHC2 1780/4885TSHR 3526/4885 |
| US-20120263659-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | TRPM8, TRPM7, TRPM2 | ZDHHC20 2278/4885ZDHHC2 3318/4885TSHR 2364/4885 |
| US-20090098076-A1 | Method For the Production of a Keratin-Binding Effector Molecule | KRT18, KRTCAP2, CUTA | ZDHHC20 576/4885ZDHHC2 1022/4885TSHR 4079/4885 |
| US-20200190052-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND COMPOSITIONS COMPRISING SUCH ACTIVE INGREDIENTS | TRPM8, TRPM7, TRPM5 | ZDHHC20 2232/4885ZDHHC2 2410/4885TSHR 1357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.