Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 3/20 | 0.50 |
| ▸ | MMP12 | P39900 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | MMP14 | P50281 | 2/20 | 0.47 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806640 | 0.88 | MMP13 (0.51) | ALDH1A1GAAKDM4ENPC1HPGD | |
| SCHEMBL7669283 | 0.87 | MEP1B (0.58) | ALDH1A1GAAKDM4ENPC1HPGD | |
| SCHEMBL7669640 | 0.87 | GHSR (0.53) | ALDH1A1MEN1KMT2APOLBCA12 | |
| SCHEMBL7690859 | 0.85 | MEP1B (0.62) | CYP2C19KMT2AMEP1BCA1MAPK1 | |
| SCHEMBL19450297 | 0.85 | MMP2 (0.56) | ALDH1A1GAAKDM4ENPC1HPGD | |
| SCHEMBL6799380 | 0.85 | ALDH1A1 (0.56) | ALDH1A1GAAKDM4ENPC1HPGD | |
| SCHEMBL5090951 | 0.85 | CA1 (0.57) | ALDH1A1GAAKDM4ENPC1HPGD | |
| SCHEMBL7582747 | 0.85 | LMNA (0.65) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7667742 | 0.85 | ALDH1A1 (0.50) | ALDH1A1GAAKDM4ENPC1HPGD | |
| SCHEMBL7673733 | 0.85 | MAPT (0.49) | ALDH1A1GAAKDM4ENPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112979510-A | Sulfonamide compounds and their use as STAT5 inhibitors | 多伦多大学管理委员会 | 2021-06-18 | — | — | CN | disclosed |