Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2872395 | 0.94 | ALDH1A1 (0.37) | ALDH1A1TSHRCNR2LMNAESR1 | |
| SCHEMBL17442484 | 0.84 | LMNA (0.36) | ALDH1A1TSHRLMNAESR1CYP1A2 | |
| SCHEMBL1304306 | 0.83 | CYP17A1 (0.36) | ALDH1A1CNR2LMNACYP1A2CYP3A4 | |
| SCHEMBL28469707 | 0.79 | ESR1 (0.54) | ALDH1A1TSHRLMNAESR1CYP1A2 | |
| SCHEMBL3794550 | 0.74 | LMNA (0.46) | ALDH1A1TSHRLMNATDP1 | |
| SCHEMBL2591636 | 0.73 | APP (0.33) | — | |
| SCHEMBL5048126 | 0.72 | FAAH (0.32) | ALDH1A1TSHR | |
| SCHEMBL7906826 | 0.67 | ALDH1A1 (0.32) | ALDH1A1LMNA | |
| SCHEMBL9332794 | 0.63 | ADRB2 (0.40) | TSHRLMNASLC6A2SLC6A3TDP1 | |
| SCHEMBL6848493 | 0.62 | PGK1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2098582-B1 | FUNCTIONAL ELECTRODE AND FUNCTIONAL ELECTROCHROMIC DEVICE | RICOH CO LTD (JP) | 2017-12-06 | — | — | EP | disclosed |
| US-7830584-B2 | Organic-inorganic composite material and method for producing the same, and functional electrode and functional device | RICOH COMPANY, LTD. (JP) | 2010-11-09 | — | — | US | disclosed |
| EP-2098582-A1 | ORGANIC INORGANIC COMPOSITE MATERIAL, PROCESS FOR PRODUCING THE SAME, AND FUNCTIONAL ELECTRODE AND FUNCTIONAL DEVICE | Ricoh Company, Ltd. (JP) | 2009-09-09 | — | — | EP | disclosed |
| US-20090002802-A1 | ORGANIC-INORGANIC COMPOSITE MATERIAL AND METHOD FOR PRODUCING THE SAME, AND FUNCTIONAL ELECTRODE AND FUNCTIONAL DEVICE | RICOH COMPANY, LTD. (JP) | 2009-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090002802-A1 | ORGANIC-INORGANIC COMPOSITE MATERIAL AND METHOD FOR PRODUCING THE SAME, AND FUNCTIONAL ELECTRODE AND FUNCTIONAL DEVICE | EPCAM, ILK, L1CAM | ALDH1A1 992/4885TSHR 4264/4885CNR2 4651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.