Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10592644 | 0.90 | LMNA (0.40) | LMNACA1CA2MMP1MMP2 | |
| Potassium Ion SCHEMBL23835503 | 0.89 | LMNA (0.30) | LMNA | |
| Lithium Ion SCHEMBL29381955 | 0.81 | LMNA (0.30) | LMNA | |
| SCHEMBL23648013 | 0.81 | LMNA (0.30) | LMNA | |
| Potassium Ion SCHEMBL23835567 | 0.77 | LMNA (0.32) | LMNA | |
| Potassium Ion SCHEMBL23835549 | 0.76 | — | — | |
| Potassium Ion SCHEMBL8010764 | 0.74 | LMNA (0.37) | LMNACA1CA2MMP1MMP2 | |
| Perflubutane SCHEMBL111514 | 0.71 | LMNA (0.54) | LMNACA1CA2MMP1MMP2 | |
| Perflubutane SCHEMBL9051673 | 0.71 | LMNA (0.54) | LMNACA1CA2MMP1MMP2 | |
| Potassium Ion SCHEMBL10969351 | 0.69 | LMNA (0.32) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121784-B | Mono-perfluoro branched ether chain oxetane series fluorine-containing polymer and preparation method thereof | 南京理工大学 | 2022-06-28 | — | — | CN | claimed |
| CN-113121779-B | Biperfluor branched ether chain oxetane series fluorine-containing polymer and preparation method thereof | 南京理工大学 | 2022-06-28 | — | — | CN | claimed |
| CN-113121779-A | Biperfluor branched ether chain oxetane series fluorine-containing polymer and preparation method thereof | 南京理工大学 | 2021-07-16 | — | — | CN | claimed |
| CN-113121784-A | Mono-perfluoro branched ether chain oxetane series fluorine-containing polymer and preparation method thereof | 南京理工大学 | 2021-07-16 | — | — | CN | claimed |
| CN-113121784-B | Mono-perfluoro branched ether chain oxetane series fluorine-containing polymer and preparation method thereof | 南京理工大学 | 2022-06-28 | — | — | CN | disclosed |
| CN-113121779-B | Biperfluor branched ether chain oxetane series fluorine-containing polymer and preparation method thereof | 南京理工大学 | 2022-06-28 | — | — | CN | disclosed |
| CN-113121779-A | Biperfluor branched ether chain oxetane series fluorine-containing polymer and preparation method thereof | 南京理工大学 | 2021-07-16 | — | — | CN | disclosed |
| CN-113121784-A | Mono-perfluoro branched ether chain oxetane series fluorine-containing polymer and preparation method thereof | 南京理工大学 | 2021-07-16 | — | — | CN | disclosed |