SCHEMBL2859684

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2868754	0.87	NFKB1 (0.40)	GAALMNAALDH1A1CYP2D6CYP2C19
	SCHEMBL2862066	0.86	LMNA (0.40)	LMNAHPGDMAPK1RECQLALDH1A1
	SCHEMBL2860006	0.83	CES2 (0.32)	ALDH1A1HSP90B1
	SCHEMBL2860340	0.83	HSP90AA1 (0.31)	HPGDALDH1A1CYP1A2CYP2D6CYP2C19
	SCHEMBL2859117	0.83	HTT (0.35)	GAALMNAALDH1A1HTTMAPT
	SCHEMBL2859963	0.82	TUBB4A (0.44)	GAALMNARECQLCYP1A2PDE4A
	SCHEMBL2858221	0.82	ALDH1A1 (0.41)	GAALMNAHPGDMAPK1ALDH1A1
	SCHEMBL4386674	0.78	ESR1 (0.39)	RECQLALDH1A1CYP1A2PDE4ACYP2C19
	SCHEMBL2862917	0.77	HPGD (0.40)	GAALMNAHPGDMAPK1RECQL
	SCHEMBL2863503	0.75	L3MBTL1 (0.40)	GAALMNAHPGDMAPK1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.