Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TRPC1 | P48995 | 2/20 | 0.38 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.38 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.38 |
| ▸ | STIM2 | Q9P246 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860103 | 0.92 | NR3C1 (0.44) | NR3C1MAPTKEAP1NFE2L2SMN1; SMN2 | |
| SCHEMBL2860939 | 0.89 | LMNA (0.45) | MAPTMEN1KMT2ACCR1TP53 | |
| SCHEMBL2860829 | 0.86 | TNKS (0.42) | MAPTMEN1KMT2AORAI1CCR1 | |
| SCHEMBL2850258 | 0.85 | MAPT (0.51) | MAPTMEN1KMT2ACCR1SMN1; SMN2 | |
| SCHEMBL2856756 | 0.84 | ACHE (0.40) | MAPTMEN1KMT2AORAI1SMN1; SMN2 | |
| SCHEMBL2853258 | 0.84 | NPY5R (0.45) | MAPTMEN1KMT2ATRPC1TRPC3 | |
| SCHEMBL2848615 | 0.84 | MAPT (0.44) | MAPTMEN1KMT2ATRPC1TRPC3 | |
| SCHEMBL2856561 | 0.83 | MAPT (0.49) | MAPTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL2859427 | 0.83 | MAPT (0.42) | MAPTMEN1KMT2ATRPC1TRPC3 | |
| SCHEMBL2854221 | 0.83 | MAPT (0.51) | NR3C1MAPTMEN1KMT2ACCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |