Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | CCNC | P24863 | 2/20 | 0.41 |
| ▸ | CDK8 | P49336 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28616300 | 0.91 | GPR183 (0.51) | LMNATP53GPR183ALDH1A1SMN1; SMN2 | |
| SCHEMBL28634881 | 0.91 | GAA (0.48) | LMNAL3MBTL1GAAMAPTTP53 | |
| SCHEMBL28620716 | 0.89 | MAPT (0.45) | LMNAL3MBTL1GAAMAPTTP53 | |
| SCHEMBL28617767 | 0.89 | L3MBTL1 (0.55) | LMNAL3MBTL1GAAMAPTTP53 | |
| SCHEMBL28627425 | 0.87 | LMNA (0.51) | LMNAL3MBTL1GAAMAPTTP53 | |
| SCHEMBL28615980 | 0.86 | POLB (0.56) | LMNAL3MBTL1GAAMAPTHTT | |
| SCHEMBL28620945 | 0.85 | GPR183 (0.50) | L3MBTL1GAAMAPTCCNCCDK8 | |
| SCHEMBL28620401 | 0.85 | GPR183 (0.55) | LMNAMAPTTP53NPC1GPR183 | |
| SCHEMBL28620396 | 0.85 | LMNA (0.48) | LMNAMAPTTP53CCNCCDK8 | |
| SCHEMBL28619727 | 0.85 | CCNC (0.46) | LMNAL3MBTL1MAPTTP53CCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440440-B | Naphthalene ring-containing 1,2, 4-oxadiazole-cinnamoyl piperazine compound and preparation method and application thereof | 贵州医科大学 | 2021-07-13 | — | — | CN | disclosed |