Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850782 | 0.86 | ALDH1A1 (0.42) | ALDH1A1MAPTTAS1R3TAS1R1TSHR | |
| SCHEMBL2850622 | 0.83 | ALDH1A1 (0.57) | ALDH1A1MAPTMAPK1MAPK14GAA | |
| SCHEMBL2856684 | 0.77 | TAS1R3 (0.58) | ALDH1A1MAPTTAS1R3TAS1R1TSHR | |
| SCHEMBL4670752 | 0.77 | CCR1 (0.49) | ALDH1A1MAPTMAPK1MAPK14GAA | |
| SCHEMBL4672609 | 0.77 | CCR1 (0.50) | ALDH1A1MAPTMAPK1MAPK14GAA | |
| SCHEMBL2850896 | 0.75 | DGAT2 (0.57) | ALDH1A1MAPTTAS1R3TAS1R1TSHR | |
| SCHEMBL2857376 | 0.75 | ALDH1A1 (0.67) | ALDH1A1MAPTMAPK1MAPK14GAA | |
| SCHEMBL2856352 | 0.74 | DGAT2 (0.56) | ALDH1A1MAPTTAS1R3TAS1R1TSHR | |
| SCHEMBL2853245 | 0.74 | ALDH1A1 (0.68) | ALDH1A1MAPTMAPK1MAPK14GAA | |
| SCHEMBL2854156 | 0.73 | ROCK2 (0.46) | ALDH1A1MAPTTSHRNPSR1KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |