Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24413984 | 0.87 | GPR84 (0.52) | GPR84ALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL28627795 | 0.85 | KDM4E (0.63) | GPR84ALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL2098856 | 0.79 | GPR84 (0.48) | GPR84ALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL30949367 | 0.79 | ALDH1A1 (0.67) | GPR84ALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL599396 | 0.79 | ALDH1A1 (0.67) | GPR84ALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL644629 | 0.79 | GPR84 (0.44) | GPR84ALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL29694174 | 0.79 | GPR84 (0.44) | GPR84ALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL7877916 | 0.77 | GPR84 (0.47) | GPR84ALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL11047294 | 0.77 | GPR84 (0.47) | GPR84ALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL7877907 | 0.77 | GPR84 (0.47) | GPR84ALDH1A1HSD17B10HIF1ACYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104530417-B | A kind of multiple functionalized H types polyethyleneglycol derivative and preparation method thereof | 厦门赛诺邦格生物科技股份有限公司 | 2017-09-08 | — | — | CN | claimed |
| CN-104530415-B | A kind of different functionalization Y types polyethyleneglycol derivative, preparation method and its bio-related substance | 厦门赛诺邦格生物科技股份有限公司 | 2017-09-01 | — | — | CN | claimed |
| CN-104530415-A | Hetero-functionalized Y-type polyethylene glycol derivative, preparation method and biologically related substance thereof | XIAMEN SINOPEG BIOTECH INC | 2015-04-22 | — | — | CN | claimed |
| CN-104530417-A | Multifunctional H-type polyethylene glycol derivative and preparation method thereof | XIAMEN SINOPEG BIOTECH INC | 2015-04-22 | — | — | CN | claimed |
| CN-104109235-A | Mono-functionalized polyethylene glycol with nitrogen atom branched center and its preparation method and biologically-relevant matter | XIAMEN SINOPEG BIOTECH CO LTD | 2014-10-22 | — | — | CN | claimed |
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2022-05-10 | — | — | US | disclosed |
| EP-3268353-B1 | PYRAZOLYL DERIVATIVES AS PEST CONTROL AGENTS | BAYER ANIMAL HEALTH GMBH (DE) | 2020-09-09 | — | — | EP | disclosed |
| US-10299478-B2 | Pyrazolyltriazolylpyridines as pesticides | BAYER ANIMAL HEALTH GMBH (DE) | 2019-05-28 | — | — | US | disclosed |
| US-10273226-B2 | Pyrazolyl-heteroarylamides as pesticides | BAYER ANIMAL HEALTH GMBH (DE) | 2019-04-30 | — | — | US | disclosed |
| EP-3157913-B1 | PYRAZOLYL TRIAZOLYL PYRIDINES AS PESTICIDE | BAYER ANIMAL HEALTH GMBH (DE) | 2019-04-17 | — | — | EP | disclosed |
| US-10202351-B2 | Pyrazolyl derivatives as pest control agents | BAYER ANIMAL HEALTH GMBH (DE) | 2019-02-12 | — | — | US | disclosed |
| CN-105073735-B | Halogen-substituted pyrazole derivatives as pest control agents | 拜耳作物科学股份公司 | 2018-08-14 | — | — | CN | disclosed |
| US-5644061-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5631375-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS, INC. (US) | 1997-05-20 | — | — | US | disclosed |
| US-5618940-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-04-08 | — | — | US | disclosed |
| CN-1128987-A | Novel intermediates for the preparation of antihistaminic piperidine derivatives | MERRELL DOW PHARMA (US) | 1996-08-14 | — | — | CN | disclosed |
| EP-0705245-A1 | NOVEL INTERMEDIATES FOR THE PREPARATION OF ANTIHISTAMINIC 4-DIPHENYLMETHYL/DIPHENYLMETHOXY PIPERIDINE DERIVATIVES | MERRELL PHARMACEUTICALS INC. (US) | 1996-04-10 | — | — | EP | disclosed |
| EP-0635004-A1 | 4-DIPHENYLMETHYL PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MERRELL PHARMACEUTICALS INC. (US) | 1995-01-25 | — | — | EP | disclosed |
| WO-1995000480-A1 | NOVEL INTERMEDIATES FOR THE PREPARATION OF ANTIHISTAMINIC 4-DIPHENYLMETHYL/DIPHENYLMETHOXY PIPERIDINE DERIVATIVES | MERRELL PHARMACEUTICALS INC. (US) | 1995-01-05 | — | — | WO | disclosed |
| WO-1993021156-A1 | 4-DIPHENYLMETHYL PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10299478-B2 | Pyrazolyltriazolylpyridines as pesticides | PRDX4, PRDX1, ATL3 | GPR84 1951/4885ALDH1A1 1058/4885HSD17B10 4597/4885 |
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | HDGF, F11, F12 | GPR84 2965/4885ALDH1A1 1582/4885HSD17B10 1914/4885 |
| US-10273226-B2 | Pyrazolyl-heteroarylamides as pesticides | CYP4Z1, NAT1, CYP4F3 | GPR84 852/4885ALDH1A1 777/4885HSD17B10 3483/4885 |
| US-10202351-B2 | Pyrazolyl derivatives as pest control agents | PIR, PDXK, CTRL | GPR84 4180/4885ALDH1A1 2607/4885HSD17B10 3598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.