Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28645581 | 0.80 | CASP1 (0.43) | CETPPPARGKDM4EALDH1A1TSHR | |
| SCHEMBL28641325 | 0.80 | L3MBTL1 (0.43) | KDM4EALDH1A1SMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL25704371 | 0.77 | FDFT1 (0.38) | CETPKDM4EALDH1A1TSHRTDP1 | |
| SCHEMBL28640739 | 0.77 | MAPT (0.44) | ALDH1A1SMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL28925133 | 0.74 | ALDH1A1 (0.42) | ALDH1A1TDP1SMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL28631825 | 0.74 | LMNA (0.41) | ALDH1A1TSHRTDP1SMN1; SMN2MAPK1 | |
| SCHEMBL28651923 | 0.72 | RIPK1 (0.35) | PPARGPPARAPPARDKDM4EALDH1A1 | |
| SCHEMBL14266924 | 0.71 | AR (0.48) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL8429259 | 0.70 | FDFT1 (0.49) | KDM4EALDH1A1TDP1SMN1; SMN2MEN1 | |
| SCHEMBL11428435 | 0.70 | DPP4 (0.46) | CETPKDM4EALDH1A1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113493419-A | EGFR tyrosine kinase inhibitor and application thereof | 南京药石科技股份有限公司 | 2021-10-12 | — | — | CN | disclosed |