Stearic Acid

Stearic Acid

SCHEMBL2863693

CCCCCCCCCCCCCCCCCC(=O)O.CCCN(CCC)CCC(N)=O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.59
PPARG P37231 7/20 0.59
PPARD Q03181 7/20 0.59
PPARA Q07869 7/20 0.59
HDAC11 Q96DB2 5/20 0.59
TSHR P16473 4/20 0.59
PTPN1 P18031 3/20 0.59
ALDH1A1 P00352 2/20 0.59
TLR2 O60603 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
FABP4 P15090 2/20 0.59
KMT2A Q03164 2/20 0.59
SLC22A6 Q4U2R8 1/20 0.59
SLC22A8 Q8TCC7 1/20 0.59
MEN1 O00255 1/20 0.59
ESR1 P03372 1/20 0.59
ALOX15 P16050 1/20 0.59
PDE4A P27815 1/20 0.59
PDE3A Q14432 1/20 0.59
HSD17B10 Q99714 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Palmitic Acid SCHEMBL28958122 1.00 GPR84 (0.59) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL722129 0.90 GPR84 (0.59) GPR84PPARGPPARDPPARAHDAC11
Decanoic Acid SCHEMBL5874581 0.89 GPR84 (0.74) GPR84PPARGPPARDPPARAHDAC11
Heptanoate SCHEMBL3412725 0.89 GPR84 (0.74) GPR84PPARGPPARDPPARAHDAC11
Octanoic Acid SCHEMBL3412675 0.89 GPR84 (0.74) GPR84PPARGPPARDPPARAHDAC11
Nonanoate SCHEMBL5875163 0.89 GPR84 (0.74) GPR84PPARGPPARDPPARAHDAC11
Undecanoate SCHEMBL21145187 0.89 GPR84 (0.74) GPR84PPARGPPARDPPARAHDAC11
Dodecanoate SCHEMBL21145283 0.89 GPR84 (0.74) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL5874513 0.89 GPR84 (0.74) GPR84PPARGPPARDPPARAHDAC11
Hexanoate SCHEMBL3412878 0.87 AKR1B1 (0.73) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3659580-B1 CLEANSER COMPOSITION KAO CORP (JP) 2025-11-05 EP claimed
US-11628130-B2 Cleanser composition KAO CORPORATION (JP) 2023-04-18 US claimed
CN-110958872-B Cleaning agent composition 花王株式会社 2023-03-14 CN claimed
US-20210145720-A1 CLEANSER COMPOSITION KAO CORPORATION (JP) 2021-05-20 US claimed
EP-3659580-A1 CLEANSER COMPOSITION Kao Corporation (JP) 2020-06-03 EP claimed
CN-110958872-A Cleaning agent composition 花王株式会社 2020-04-03 CN claimed
EP-3659580-B1 CLEANSER COMPOSITION KAO CORP (JP) 2025-11-05 EP disclosed
WO-2025047878-A1 HAIR DYE COMPOSITION COMPRISING BLUE DYES, UREA AND A CATIONIC SURFACTANT HENKEL AG & CO. KGAA (DE) 2025-03-06 WO disclosed
WO-2025047874-A1 HAIR DYE COMPOSITION COMPRISING BLUE DYES, BASIC RED OR YELLOW DYES AND A CATIONIC SURFACTANT HENKEL AG & CO. KGAA (DE) 2025-03-06 WO disclosed
CN-119060793-A Detergent composition for tableware cleaning machine and detergent article with squeeze container 狮王株式会社 2024-12-03 CN disclosed
WO-2024070386-A1 HAIR TREATMENT AGENT OR HEAD DECORATION PRODUCT FIBER TREATMENT AGENT 花王株式会社 2024-04-04 WO disclosed
US-11628130-B2 Cleanser composition KAO CORPORATION (JP) 2023-04-18 US disclosed
US-20210145720-A1 CLEANSER COMPOSITION KAO CORPORATION (JP) 2021-05-20 US disclosed
EP-3659580-A1 CLEANSER COMPOSITION Kao Corporation (JP) 2020-06-03 EP disclosed
WO-2020067448-A1 NON-FLUORINATED BLOCK COPOLYMER ダイキン工業株式会社 2020-04-02 WO disclosed
WO-2020044956-A1 COSMETIC AND CLEANSER 株式会社 資生堂 2020-03-05 WO disclosed
EP-2151232-B1 OXIDATIVE HAIR DYE COMPOSITION KAO CORP (JP) 2017-04-12 EP disclosed
US-7842101-B2 Oxidative hair dye composition KAO CORPORATION (JP) 2010-11-30 US disclosed
US-20100154135-A1 OXIDATIVE HAIR DYE COMPOSITION KAO CORPORATION (JP) 2010-06-24 US disclosed
EP-2151232-A1 OXIDATIVE HAIR DYE COMPOSITION Kao Corporation (JP) 2010-02-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100154135-A1 OXIDATIVE HAIR DYE COMPOSITION COXFA4, COXFA4L2, NDUFAB1 GPR84 1793/4885PPARG 1399/4885PPARD 858/4885
US-20210145720-A1 CLEANSER COMPOSITION ADH1C, WASHC4, AP2S1 GPR84 694/4885PPARG 1669/4885PPARD 2124/4885
US-11628130-B2 Cleanser composition ADH1C, SMURF1, DEGS1 GPR84 745/4885PPARG 1454/4885PPARD 1600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.