Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.59 |
| ▸ | PPARG | P37231 | 7/20 | 0.59 |
| ▸ | PPARD | Q03181 | 7/20 | 0.59 |
| ▸ | PPARA | Q07869 | 7/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.59 |
| ▸ | FABP4 | P15090 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TLR2 | O60603 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.59 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | PDE4A | P27815 | 1/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Stearic Acid SCHEMBL2863693 | 0.90 | GPR84 (0.59) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL28958122 | 0.90 | GPR84 (0.59) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL7783078 | 0.87 | GRM8 (0.47) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL20142614 | 0.85 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL20142314 | 0.85 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octadecanoic Acid Amide SCHEMBL2026272 | 0.85 | SOAT1 (0.55) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL20142564 | 0.85 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL20142749 | 0.85 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL20142872 | 0.85 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL20142518 | 0.85 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3659580-B1 | CLEANSER COMPOSITION | KAO CORP (JP) | 2025-11-05 | — | — | EP | claimed |
| US-11628130-B2 | Cleanser composition | KAO CORPORATION (JP) | 2023-04-18 | — | — | US | claimed |
| CN-110958872-B | Cleaning agent composition | 花王株式会社 | 2023-03-14 | — | — | CN | claimed |
| CN-109549860-B | Preparation method of positively charged liposome and charged liposome | J网络公司 | 2022-06-07 | — | — | CN | claimed |
| US-20210145720-A1 | CLEANSER COMPOSITION | KAO CORPORATION (JP) | 2021-05-20 | — | — | US | claimed |
| US-11000477-B2 | Preparing method for positively-electrified charged niosome, and charged niosome | J-NETWORK, INC. (US) | 2021-05-11 | — | — | US | claimed |
| EP-3659580-A1 | CLEANSER COMPOSITION | Kao Corporation (JP) | 2020-06-03 | — | — | EP | claimed |
| CN-110958872-A | Cleaning agent composition | 花王株式会社 | 2020-04-03 | — | — | CN | claimed |
| EP-3459525-A1 | PREPARING METHOD FOR POSITIVELY-ELECTRIFIED CHARGED NIOSOME, AND CHARGED NIOSOME | J-Network, Inc. (US) | 2019-03-27 | — | — | EP | claimed |
| EP-3659580-B1 | CLEANSER COMPOSITION | KAO CORP (JP) | 2025-11-05 | — | — | EP | disclosed |
| WO-2025047878-A1 | HAIR DYE COMPOSITION COMPRISING BLUE DYES, UREA AND A CATIONIC SURFACTANT | HENKEL AG & CO. KGAA (DE) | 2025-03-06 | — | — | WO | disclosed |
| WO-2025047874-A1 | HAIR DYE COMPOSITION COMPRISING BLUE DYES, BASIC RED OR YELLOW DYES AND A CATIONIC SURFACTANT | HENKEL AG & CO. KGAA (DE) | 2025-03-06 | — | — | WO | disclosed |
| CN-119060793-A | Detergent composition for tableware cleaning machine and detergent article with squeeze container | 狮王株式会社 | 2024-12-03 | — | — | CN | disclosed |
| WO-2024070386-A1 | HAIR TREATMENT AGENT OR HEAD DECORATION PRODUCT FIBER TREATMENT AGENT | 花王株式会社 | 2024-04-04 | — | — | WO | disclosed |
| US-8273336-B2 | Hair treatment composition | SHISEIDO COMPANY, LTD. (JP) | 2012-09-25 | — | — | US | disclosed |
| US-20120052032-A1 | HAIR TREATMENT COMPOSITION | SHISEIDO COMPANY, LTD. (JP) | 2012-03-01 | — | — | US | disclosed |
| EP-2404592-A1 | HAIR TREATMENT COMPOSITION | Shiseido Company, Ltd. (JP) | 2012-01-11 | — | — | EP | disclosed |
| US-7842101-B2 | Oxidative hair dye composition | KAO CORPORATION (JP) | 2010-11-30 | — | — | US | disclosed |
| US-20100154135-A1 | OXIDATIVE HAIR DYE COMPOSITION | KAO CORPORATION (JP) | 2010-06-24 | — | — | US | disclosed |
| EP-2151232-A1 | OXIDATIVE HAIR DYE COMPOSITION | Kao Corporation (JP) | 2010-02-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100154135-A1 | OXIDATIVE HAIR DYE COMPOSITION | COXFA4, COXFA4L2, NDUFAB1 | GPR84 1793/4885PPARG 1399/4885PPARD 858/4885 |
| US-20120052032-A1 | HAIR TREATMENT COMPOSITION | POLR1C, SHH, DNMT1 | GPR84 1350/4885PPARG 2798/4885PPARD 2919/4885 |
| US-20210145720-A1 | CLEANSER COMPOSITION | ADH1C, WASHC4, AP2S1 | GPR84 694/4885PPARG 1669/4885PPARD 2124/4885 |
| US-11628130-B2 | Cleanser composition | ADH1C, SMURF1, DEGS1 | GPR84 745/4885PPARG 1454/4885PPARD 1600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.