Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | VCP | P55072 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78988 | 0.86 | KDR (0.45) | RAB9ANPC1KDRCHEK1KDM4E | |
| SCHEMBL3959785 | 0.84 | KDR (0.44) | RAB9ANPC1KDRCHEK1KDM4E | |
| SCHEMBL15758299 | 0.77 | MAPT (0.57) | RAB9ANPC1KDRCHEK1KDM4E | |
| Valine SCHEMBL2174939 | 0.75 | ALOX5 (0.36) | RAB9ANPC1KDRCHEK1PARP1 | |
| SCHEMBL2986723 | 0.74 | RIPK1 (0.44) | DAOCYP19A1ITK | |
| SCHEMBL8685658 | 0.72 | CHEK1 (0.40) | RAB9ANPC1KDRCHEK1KDM4E | |
| SCHEMBL8685683 | 0.72 | KDR (0.40) | RAB9ANPC1KDRCHEK1KDM4E | |
| SCHEMBL303331 | 0.71 | ALDH1A1 (0.51) | MAPTHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL31060695 | 0.69 | RAB9A (0.46) | RAB9ANPC1KDRCHEK1KDM4E | |
| SCHEMBL856332 | 0.68 | KDR (0.51) | RAB9ANPC1KDRCHEK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563307-B | Method for synthesizing alpha-cyclic amine maleimide hybrid | 河南师范大学 | 2022-05-17 | — | — | CN | claimed |
| CN-113563307-A | Method for synthesizing alpha-cyclic amine maleimide hybrid | 河南师范大学 | 2021-10-29 | — | — | CN | claimed |
| CN-113563307-B | Method for synthesizing alpha-cyclic amine maleimide hybrid | 河南师范大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-113563307-A | Method for synthesizing alpha-cyclic amine maleimide hybrid | 河南师范大学 | 2021-10-29 | — | — | CN | disclosed |