Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2884210 | 0.81 | CYP2A6 (0.50) | CYP2A6ALDH1A1ALOX15MAPK1TDP1 | |
| SCHEMBL3757571 | 0.73 | CYP2A6 (0.57) | CYP2A6ALDH1A1ALOX15MAPK1TDP1 | |
| SCHEMBL2154365 | 0.71 | LMNA (0.53) | CYP2A6ALDH1A1ALOX15MAPK1TDP1 | |
| SCHEMBL4276353 | 0.71 | CYP2A6 (0.53) | CYP2A6ALDH1A1ALOX15MAPK1TDP1 | |
| SCHEMBL18508 | 0.71 | — | — | |
| SCHEMBL11916255 | 0.69 | CYP2A6 (0.50) | CYP2A6ALDH1A1ALOX15MAPK1TDP1 | |
| SCHEMBL11770595 | 0.69 | CYP2A6 (0.50) | CYP2A6ALDH1A1ALOX15MAPK1TDP1 | |
| SCHEMBL2153517 | 0.69 | CA1 (0.38) | CA2CA1CES2CES1TAAR1 | |
| SCHEMBL28648779 | 0.69 | CYP2A6 (0.50) | CYP2A6ALDH1A1ALOX15MAPK1TDP1 | |
| SCHEMBL667708 | 0.69 | ACHE (0.50) | CYP2A6ALDH1A1TDP1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0340985-B1 | PROCESS FOR PREPARING TRANS-2,2-DIMETHYL-3-(2,2-DIHALOVINYL)-CYCLOPROPANE CARBOXYLIC ACID HALIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-4954651-A | Process for preparing trans-2,2-dimethyl-3-(2,2-dihalovinyl)-cyclopropane carboxylic acid halide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-09-04 | — | — | US | disclosed |
| EP-0340985-A1 | Process for preparing trans-2,2-dimethyl-3-(2,2-dihalovinyl)-cyclopropane carboxylic acid halide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-11-08 | — | — | EP | disclosed |
| US-4680342-A | Flame resistant alkenyl aromatic compounds and polymers containing chemically bonded phosphorus and blends with polyphenylene ether | GENERAL ELECTRIC COMPANY (US) | 1987-07-14 | — | — | US | disclosed |
| EP-0147724-A2 | Flame resistant alkenyl aromatic compounds and polymers containing chemically bonded phosphorus and blends with polyphenylene ether | GENERAL ELECTRIC COMPANY (US) | 1985-07-10 | — | — | EP | disclosed |
| US-3975447-A | Preparation of aromatic phosphine oxides by reaction of diarylhalophosphine and benzylic halide | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-08-17 | — | — | US | disclosed |