Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | PRKX | P51817 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | MELK | Q14680 | 1/20 | 0.38 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.38 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28668104 | 0.87 | GLS (0.43) | GLSGSK3BCDC7DAPK3ROCK2 | |
| SCHEMBL28650916 | 0.83 | GAA (0.38) | GSK3BCDC7DAPK3PAK4CDK2 | |
| SCHEMBL30271518 | 0.83 | GLS (0.38) | GLSGSK3BCDC7DAPK3ROCK2 | |
| SCHEMBL28664307 | 0.82 | HPGD (0.38) | ALDH1A1CNR1 | |
| SCHEMBL28654355 | 0.81 | PTGS2 (0.33) | CTSLCTSS | |
| SCHEMBL28649850 | 0.81 | KCNH2 (0.35) | CTSLCTSS | |
| SCHEMBL28654148 | 0.79 | BCAT1 (0.42) | GLSGSK3BCLK2DYRK1A | |
| SCHEMBL28929387 | 0.78 | TAS2R8 (0.38) | GSK3BDYRK1ATAS2R8GAAALDH1A1 | |
| SCHEMBL28670333 | 0.71 | MMP2 (0.42) | ALDH1A1CTSLCTSS | |
| SCHEMBL28673180 | 0.68 | KDM4E (0.42) | GAAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692276-A | NURR1 receptor modulators | 加利福尼亚大学董事会 | 2021-11-23 | — | — | CN | disclosed |