Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.38 |
| ▸ | WNT1 | P04628 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.35 |
| ▸ | WNT3A | P56704 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KLK3 | P07288 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28664289 | 0.86 | TAS2R8 (0.41) | TAS2R8WNT1GSK3BDYRK1ANAMPT | |
| SCHEMBL30271513 | 0.82 | TAS2R8 (0.39) | TAS2R8WNT1GSK3BDYRK1ANAMPT | |
| SCHEMBL28664307 | 0.82 | HPGD (0.38) | POLBMAPTPTGS2MEN1ALDH1A1 | |
| SCHEMBL28649850 | 0.79 | KCNH2 (0.35) | PTGS2MEN1KMT2A | |
| SCHEMBL28654355 | 0.79 | PTGS2 (0.33) | PTGS2 | |
| SCHEMBL28650916 | 0.79 | GAA (0.38) | GSK3BDYRK1AMAPTMEN1ALDH1A1 | |
| SCHEMBL28654148 | 0.78 | BCAT1 (0.42) | WNT1GSK3BDYRK1ANAMPT | |
| SCHEMBL28650412 | 0.78 | GLS (0.38) | TAS2R8GSK3BDYRK1AALDH1A1GAA | |
| SCHEMBL28670333 | 0.69 | MMP2 (0.42) | PTGS2ALDH1A1KMT2A | |
| SCHEMBL28655200 | 0.67 | HPGD (0.43) | POLBMAPTMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692276-A | NURR1 receptor modulators | 加利福尼亚大学董事会 | 2021-11-23 | — | — | CN | disclosed |