Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21952069 | 0.87 | ALDH1A1 (0.44) | TP53KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL29798375 | 0.87 | ALDH1A1 (0.44) | TP53KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL24019587 | 0.84 | ALOX5 (0.39) | TP53KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL28659325 | 0.83 | KMT2A (0.51) | TP53KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL31396338 | 0.75 | ALPL (0.43) | TP53KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL28673736 | 0.73 | HPGD (0.53) | TP53KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL28670742 | 0.72 | HPGD (0.50) | TP53KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL21952011 | 0.72 | LMNA (0.47) | KMT2AMEN1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL28666198 | 0.72 | ALDH1A1 (0.43) | TP53KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL28664794 | 0.71 | HPGD (0.49) | KMT2AMEN1ALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115768422-A | Ubiquitin ligase inhibitors for the treatment of cancer | 诺沃亚桑托斯教授基金会 | 2023-03-07 | — | — | CN | disclosed |
| CN-113677340-A | Compounds that selectively and efficiently inhibit Hakai-mediated ubiquitination as anti-cancer agents | 诺沃亚桑托斯教授基金会 | 2021-11-19 | — | — | CN | disclosed |