Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28688354 | 0.97 | FPR2 (0.40) | FPR2NOD1CA2MMECHRM1 | |
| SCHEMBL28686957 | 0.82 | POLB (0.43) | CA2MMEKMT2ANFKB1FOLH1 | |
| Lithium Ion SCHEMBL28670629 | 0.82 | POLB (0.43) | CA2MMEKMT2ANFKB1FOLH1 | |
| SCHEMBL3282950 | 0.77 | FPR2 (0.46) | FPR2NOD1CA2MMECHRM1 | |
| SCHEMBL2172444 | 0.77 | FPR2 (0.46) | FPR2NOD1CA2MMECHRM1 | |
| SCHEMBL12291691 | 0.77 | FPR2 (0.46) | FPR2NOD1CA2MMECHRM1 | |
| Potassium Ion SCHEMBL10934871 | 0.77 | CA12 (0.44) | FPR2NOD1CA2MMECHRM1 | |
| Hydrochloric Acid SCHEMBL32661728 | 0.76 | FPR2 (0.45) | FPR2NOD1CA2MMECHRM1 | |
| SCHEMBL7641648 | 0.76 | FPR2 (0.45) | FPR2NOD1MMECHRM1AKR1A1 | |
| SCHEMBL2107300 | 0.74 | FPR2 (0.44) | FPR2NOD1CA2MMECHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110035829-B | Depressant composition and method for depressing gangue sulfide minerals during flotation of sulfide ores | 塞特工业公司 | 2021-12-24 | — | — | CN | disclosed |