Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6302571 | 0.90 | TSHR (0.50) | TSHRALDH1A1BRD4RAB9ANPC1 | |
| SCHEMBL32671905 | 0.89 | TSHR (0.55) | TSHRALDH1A1BRD4RAB9ANPC1 | |
| SCHEMBL2674793 | 0.86 | L3MBTL1 (0.47) | TSHRALDH1A1RAB9ANPC1L3MBTL1 | |
| SCHEMBL133464 | 0.79 | ALDH1A1 (0.57) | TSHRALDH1A1BRD4L3MBTL1KMT2A | |
| SCHEMBL2341656 | 0.79 | MAPT (0.51) | ALDH1A1BRD4L3MBTL1MAPT | |
| SCHEMBL7590440 | 0.79 | BRD4 (0.45) | TSHRALDH1A1BRD4RAB9ANPC1 | |
| SCHEMBL25168045 | 0.78 | L3MBTL1 (0.46) | TSHRALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL3447293 | 0.78 | CNR2 (0.46) | TSHRALDH1A1RAB9ANPC1L3MBTL1 | |
| SCHEMBL4698252 | 0.78 | SMN1; SMN2 (0.47) | TSHRALDH1A1L3MBTL1KMT2AGAA | |
| SCHEMBL25736832 | 0.78 | L3MBTL1 (0.46) | TSHRALDH1A1L3MBTL1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922394-B | 3-tetrazolyl-benzene-1, 2-disulfonamide derivatives as metallo-beta-lactamase inhibitors | 默沙东公司 | 2021-07-13 | — | — | CN | disclosed |