Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 4/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.36 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19212401 | 0.85 | P2RY12 (0.54) | P2RY12KEAP1NFE2L2 | |
| SCHEMBL19212409 | 0.77 | P2RY12 (0.57) | P2RY12MAPTCXCR3PDE1BUSP28 | |
| SCHEMBL28931799 | 0.76 | NR1H2 (0.51) | ABCB1MAPTHDAC8NR1H2NR1H3 | |
| SCHEMBL21457818 | 0.74 | BACE1 (0.48) | MAPTKEAP1NFE2L2SMN1; SMN2 | |
| SCHEMBL28697404 | 0.73 | ABCB1 (0.43) | ABCB1MAPTNR1H2NR1H3PTPN1 | |
| SCHEMBL28683481 | 0.72 | PDK1 (0.39) | MAPTSMN1; SMN2 | |
| SCHEMBL29578198 | 0.72 | KEAP1 (0.42) | ABCB1MAPTKEAP1NFE2L2HDAC1 | |
| SCHEMBL19210927 | 0.72 | KEAP1 (0.42) | ABCB1MAPTKEAP1NFE2L2HDAC1 | |
| SCHEMBL28672741 | 0.71 | KEAP1 (0.41) | ABCB1MAPTKEAP1NFE2L2SMN1; SMN2 | |
| SCHEMBL28690482 | 0.70 | SIGMAR1 (0.51) | MAPTNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071560-B | Thienopyridine carboxamides as ubiquitin-specific protease inhibitors | 瓦洛健康公司 | 2022-01-14 | — | — | CN | disclosed |