SCHEMBL2868519

SCHEMBL2868519

O=C1C=CC(=NNc2ccccc2)C=C1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.44
HTT P42858 2/20 0.44
DEPTOR Q8TB45 1/20 0.44
GFER P55789 2/20 0.39
TDP1 Q9NUW8 4/20 0.38
TSHR P16473 2/20 0.38
CYP1A1 P04798 1/20 0.38
CYP1B1 Q16678 1/20 0.38
MEN1 O00255 5/20 0.37
KMT2A Q03164 5/20 0.37
GAA P10253 4/20 0.37
MAPT P10636 4/20 0.37
HPGD P15428 1/20 0.37
ALOX12 P18054 1/20 0.37
MCL1 Q07820 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37
NOX1 Q9Y5S8 1/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21995787 0.86 MAPT (0.44) ALDH1A1HTTTDP1TSHRCYP1A1
SCHEMBL2682056 0.80 MAPT (0.46) ALDH1A1HTTDEPTORGFERTDP1
SCHEMBL29209193 0.74 MEN1 (0.44) ALDH1A1HTTTDP1TSHRMEN1
SCHEMBL17088267 0.74 KMT2A (0.46) ALDH1A1HTTGFERTDP1MEN1
SCHEMBL2868736 0.73 RAB9A (0.55) ALDH1A1TDP1MEN1KMT2AGAA
SCHEMBL11876923 0.72 KMT2A (0.45) ALDH1A1HTTTDP1MEN1KMT2A
Diphenylamine SCHEMBL9632812 0.72 HSD17B10 (0.67) ALDH1A1HTTGFERTDP1TSHR
SCHEMBL341192 0.72 ALDH1A1 (0.39) ALDH1A1HTTDEPTORGFERTDP1
SCHEMBL11689083 0.69 ALDH1A1 (0.53) ALDH1A1HTTGFERTDP1TSHR
SCHEMBL1813567 0.67 TXNRD1 (0.47) ALDH1A1TDP1MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101204357-B Cosmetic product for dry-dyeing hair, applications and method of using same OU LAIYA 2012-07-18 CN claimed
US-7611545-B2 Cosmetic article and process for dry dyeing keratin materials L'OREAL S.A. (FR) 2009-11-03 US claimed
US-20080244837-A1 Cosmetic article and process for dry dyeing keratin materials L'OREAL S.A. (FR) 2008-10-09 US claimed
EP-1964539-A1 Cosmetic article for dyeing dry hair, its use, method of implementing said article L'Oréal (FR) 2008-09-03 EP claimed
US-20080148496-A1 Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Dye, Composition Comprising the Said Dye and Its Method of Preparation L'OREAL S.A. (FR) 2008-06-26 US claimed
US-10589003-B2 Methods for coating surfaces with antimicrobial agents THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2020-03-17 US disclosed
US-20180303977-A1 METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2018-10-25 US disclosed
WO-2018012606-A1 REACTION ACCELERATOR キッコーマン株式会社 2018-01-18 WO disclosed
CN-104031766-B A kind of mahogany furniture cleaning agent 滁州斯迈特复合材料有限公司 2016-08-03 CN disclosed
CN-104031766-A Redwood furniture cleaning agent CHUZHOU SMET COMPOUND MATERIALS CO LTD 2014-09-10 CN disclosed
CN-101204357-B Cosmetic product for dry-dyeing hair, applications and method of using same OU LAIYA 2012-07-18 CN disclosed
US-7722680-B2 Dyeing of human keratin materials by dry thermal transfer of a direct dye, composition comprising the said dye and its method of preparation L'OREAL S.A. (FR) 2010-05-25 US disclosed
US-7651661-B2 Medical devices with broad spectrum antimicrobial activity BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-01-26 US disclosed
US-7611545-B2 Cosmetic article and process for dry dyeing keratin materials L'OREAL S.A. (FR) 2009-11-03 US disclosed
US-20080244837-A1 Cosmetic article and process for dry dyeing keratin materials L'OREAL S.A. (FR) 2008-10-09 US disclosed
EP-1964539-A1 Cosmetic article for dyeing dry hair, its use, method of implementing said article L'Oréal (FR) 2008-09-03 EP disclosed
US-20080183152-A1 MEDICAL DEVICES WITH BROAD SPECTRUM ANTIMICROBIAL ACTIVITY RAAD ISSAM 2008-07-31 US disclosed
US-20080148496-A1 Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Dye, Composition Comprising the Said Dye and Its Method of Preparation L'OREAL S.A. (FR) 2008-06-26 US disclosed
US-20070154621-A1 METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2007-07-05 US disclosed
US-20050197634-A1 Methods for coating and impregnating medical devices with antiseptic compositions BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2005-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10589003-B2 Methods for coating surfaces with antimicrobial agents CUTA, CD63, CDC37 ALDH1A1 1120/4885HTT 4352/4885DEPTOR 932/4885
US-20080244837-A1 Cosmetic article and process for dry dyeing keratin materials KRT18, CUTA, DSG1 ALDH1A1 844/4885HTT 2019/4885DEPTOR 2823/4885
US-20180303977-A1 METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS CUTA, CD63, CDC37 ALDH1A1 1120/4885HTT 4352/4885DEPTOR 932/4885
US-20080148496-A1 Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Dye, Composition Comprising the Said Dye and Its Method of Preparation KRT18, IK, DSG1 ALDH1A1 911/4885HTT 2013/4885DEPTOR 3002/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.