SCHEMBL341192

SCHEMBL341192

O=C1C=C/C(=N\Nc2ccccc2)C(O)=C1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.39
HTT P42858 1/20 0.39
GAA P10253 10/20 0.38
KMT2A Q03164 7/20 0.38
MEN1 O00255 6/20 0.38
GFER P55789 4/20 0.38
DEPTOR Q8TB45 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
MAPT P10636 8/20 0.35
SMN1; SMN2 Q16637 6/20 0.35
TDP1 Q9NUW8 3/20 0.35
KDM4E B2RXH2 1/20 0.35
XDH P47989 1/20 0.35
HPGD P15428 2/20 0.34
LMNA P02545 2/20 0.33
ALOX12 P18054 2/20 0.33
MCL1 Q07820 1/20 0.33
POLB P06746 1/20 0.33
HSP90AA1 P07900 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2868519 0.72 ALDH1A1 (0.44) ALDH1A1HTTGAAKMT2AMEN1
SCHEMBL30702589 0.69 KMT2A (0.36) ALDH1A1HTTGAAKMT2AMEN1
SCHEMBL11486250 0.66 ALDH1A1 (0.33) ALDH1A1TDP1POLBMAOAMAOB
SCHEMBL18752710 0.66 DEPTOR (0.41) ALDH1A1HTTGAAKMT2AMEN1
SCHEMBL14506042 0.63 GAA (0.47) ALDH1A1HTTGAAKMT2AMEN1
SCHEMBL901064 0.62 ALDH1A1 (0.41) ALDH1A1HTTGAAKMT2AMEN1
Phenol SCHEMBL28096443 0.62 TDP1 (0.48) ALDH1A1KMT2AMEN1NPC1RAB9A
SCHEMBL14394430 0.62 DEPTOR (0.41) ALDH1A1HTTGAAKMT2AMEN1
Diphenylamine SCHEMBL9632812 0.61 HSD17B10 (0.67) ALDH1A1HTTGAAKMT2AMEN1
SCHEMBL21995787 0.61 MAPT (0.44) ALDH1A1HTTKMT2AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101204357-B Cosmetic product for dry-dyeing hair, applications and method of using same OU LAIYA 2012-07-18 CN claimed
US-7611545-B2 Cosmetic article and process for dry dyeing keratin materials L'OREAL S.A. (FR) 2009-11-03 US claimed
US-20080244837-A1 Cosmetic article and process for dry dyeing keratin materials L'OREAL S.A. (FR) 2008-10-09 US claimed
EP-1964539-A1 Cosmetic article for dyeing dry hair, its use, method of implementing said article L'Oréal (FR) 2008-09-03 EP claimed
US-20080148496-A1 Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Dye, Composition Comprising the Said Dye and Its Method of Preparation L'OREAL S.A. (FR) 2008-06-26 US claimed
EP-2710996-B1 Sunscreen compositions comprising colour pigments BASF SE (DE) 2022-08-17 EP disclosed
US-11384033-B2 Compositions with improved urease-inhibiting effect comprising (thio)phosphoric acid triamide and further compounds such as amines and colorants BASF SE (DE) 2022-07-12 US disclosed
CN-107108388-B Composition comprising (thio) phosphoric triamide and other compounds such as amines and colorants with improved urease-inhibiting effect 巴斯夫欧洲公司 2021-02-26 CN disclosed
CN-112374933-A Composition comprising (thio) phosphoric triamide and other compounds such as amines and colorants with improved urease-inhibiting effect 巴斯夫欧洲公司 2021-02-19 CN disclosed
EP-3763691-A1 COMPOSITIONS WITH IMPROVED UREASE-INHIBITING EFFECT COMPRISING (THIO)PHOSPHORIC ACID TRIAMIDE AND FURTHER COMPOUNDS SUCH AS AMINES AND COLORANTS BASF SE (DE) 2021-01-13 EP disclosed
EP-3763692-A1 COMPOSITIONS WITH IMPROVED UREASE-INHIBITING EFFECT COMPRISING (THIO) PHOSPHORIC ACID TRIAMIDE AND FURTHER COMPOUNDS SUCH AS AMINES AND COLORANTS BASF SE (DE) 2021-01-13 EP disclosed
EP-3725756-A2 COMPOSITIONS WITH IMPROVED UREASE-INHIBITING EFFECT COMPRISING AMINES, OR COLORANTS, AND AN ADDUCT OF THE THREE COMPOUNDS N-(N-BUTYL) THIOPHOSPHORIC ACID TRIAMIDE (NBPT), UREA, AND FORMALDEHYDE BASF SE (DE) 2020-10-21 EP disclosed
US-20030143112-A1 Colorimetric artificial nose having an array of dyes and method for artificial olfaction BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2003-07-31 US disclosed
US-20030068347-A1 Use of microbially encapsulated meterials in cosmetic end formulations CIBA SPECIALTY CHEMICALS CORP. 2003-04-10 US disclosed
EP-1246602-A2 USE OF MICROBIALLY ENCAPSULATED MATERIALS IN COSMETIC END FORMULATIONS Ciba SC Holding AG (CH) 2002-10-09 EP disclosed
US-20020106390-A1 Use of nanodispersions in cosmetic end formulations HUGLIN DIETMAR (DE) 2002-08-08 US disclosed
WO-2001051013-A2 USE OF MICROBIALLY ENCAPSULATED MATERIALS IN COSMETIC END FORMULATIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-07-19 WO disclosed
EP-0956851-A1 Use of nanotopes in cosmetic products Ciba SC Holding AG (CH) 1999-11-17 EP disclosed
US-5807604-A SOLVENT MIXTURE COMPRISING TARTRAZINE YELLOW AND AQUEOUS ETHYLENE GLYCOL PRESERVED BOTANICALS, INC. (US) 1998-09-15 US disclosed
US-5693361-A SOAKING NATURAL PLANT MATERIALS IN AQUEOUS SOLUTION CONTAINING ETHYLENE GLYCOL AND DISSOLVED CARBON DIOXIDE, FOR DECORATIONS PRESERVED BOTANICALS, INC. (US) 1997-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030068347-A1 Use of microbially encapsulated meterials in cosmetic end formulations CUTA, MGLL, TMEM205 ALDH1A1 1906/4885HTT 1398/4885GAA 155/4885
US-20020106390-A1 Use of nanodispersions in cosmetic end formulations NPC1L1, LIPA, CUTA ALDH1A1 414/4885HTT 3688/4885GAA 695/4885
US-11384033-B2 Compositions with improved urease-inhibiting effect comprising (thio)phosphoric acid triamide and further compounds such as amines and colorants SLC14A1, XDH, PNP ALDH1A1 1062/4885HTT 2343/4885GAA 510/4885
US-20080244837-A1 Cosmetic article and process for dry dyeing keratin materials KRT18, CUTA, DSG1 ALDH1A1 844/4885HTT 2019/4885GAA 1425/4885
US-20080148496-A1 Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Dye, Composition Comprising the Said Dye and Its Method of Preparation KRT18, IK, DSG1 ALDH1A1 911/4885HTT 2013/4885GAA 2808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.