Robenidine

Robenidine

SCHEMBL28694173

N/C(=N\N=C\c1ccc(Cl)cc1)N/N=C/c1ccc(Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 4/20 0.69
▸ RAB9A P51151 4/20 0.69
▸ MAPT P10636 2/20 0.69
▸ MEN1 O00255 1/20 0.69
▸ TAAR1 Q96RJ0 1/20 0.69
▸ GRIN2D O15399 4/20 0.64
▸ GRIN3B O60391 4/20 0.64
▸ GRIN1 Q05586 4/20 0.64
▸ GRIN2A Q12879 4/20 0.64
▸ GRIN2B Q13224 4/20 0.64
▸ GRIN2C Q14957 4/20 0.64
▸ GRIN3A Q8TCU5 4/20 0.64
▸ CA1 P00915 1/20 0.49
▸ CA2 P00918 1/20 0.49
▸ CA4 P22748 1/20 0.49
▸ CA9 Q16790 1/20 0.49
▸ KDM4E B2RXH2 3/20 0.49
▸ F2 P00734 1/20 0.48
▸ FURIN P09958 1/20 0.48
▸ CHIA Q9BZP6 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Robenidine SCHEMBL571510 1.00 KMT2A (0.69) KMT2ARAB9AMAPTMEN1TAAR1
Robenidine SCHEMBL17536045 1.00 KMT2A (0.69) KMT2ARAB9AMAPTMEN1TAAR1
Robenidine SCHEMBL23858311 1.00 KMT2A (0.69) KMT2ARAB9AMAPTMEN1TAAR1
Robenidine SCHEMBL23858319 0.98 KMT2A (0.72) KMT2ARAB9AMAPTMEN1TAAR1
Robenidine SCHEMBL25169352 0.98 KMT2A (0.72) KMT2ARAB9AMAPTMEN1TAAR1
Robenidine SCHEMBL30371560 0.98 KMT2A (0.72) KMT2ARAB9AMAPTMEN1TAAR1
Robenidine SCHEMBL23858320 0.98 KMT2A (0.72) KMT2ARAB9AMAPTMEN1TAAR1
Robenidine SCHEMBL30051666 0.82 KMT2A (0.55) KMT2ARAB9AMAPTMEN1TAAR1
Hydrochloric Acid SCHEMBL11850203 0.81 GRIN2D (0.59) KMT2ARAB9AMAPTMEN1TAAR1
Hydrochloric Acid SCHEMBL11838603 0.81 GRIN2D (0.59) KMT2ARAB9AMAPTMEN1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2683395-B2 USE OF LOW DOSE IL-2 FOR TREATING TYPE 1 DIABETES HOPITAUX PARIS ASSIST PUBLIQUE (FR) 2026-05-20 — — EP disclosed
EP-3443979-B2 IL-2 DOSAGE REGIMEN FOR TREATING SYSTEMIC LUPUS ERYTHEMATOSUS HOPITAUX PARIS ASSIST PUBLIQUE (FR) 2026-05-20 — — EP disclosed
EP-4710966-A1 AUTOINJECTOR AND METHOD OF RECONSTITUTING AN AUTOINJECTOR medmix Switzerland AG (CH) 2026-03-18 — — EP disclosed
EP-4691556-A2 HUMANIZED ANTI-ACTH ANTIBODIES AND USE THEREOF H. Lundbeck A/S (DK) 2026-02-11 — — EP disclosed
US-20260001874-A1 DIHYDROQUINAZOLINONES EXHIBITING IMPROVED PROTECTIVE ACTIVITY AGAINST INTRACELLULARLY ACTING TOXINS AND INTRACELLULAR VIRUSES AND BACTERIA Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2026-01-01 — — US disclosed
US-12491232-B2 Low dose IL-2 for treating autoimmune-related or inflammatory disorders INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2025-12-09 — — US disclosed
EP-3835319-B1 HUMANIZED ANTI-ACTH ANTIBODIES AND USE THEREOF H LUNDBECK AS (DK) 2025-11-19 — — EP disclosed
US-20250346567-A1 SUBSTITUTED PYRIDINE AND PHENYL COMPOUNDS PFIZER INC. (US) 2025-11-13 — — US disclosed
US-12467053-B2 Hybrid immunoglobulins with moving parts BIOMOLECULAR HOLDINGS LLC (US) 2025-11-11 — — US disclosed
US-12421269-B2 SGLT2/DPP4 inhibitor and application thereof CGENETECH (SUZHOU, CHINA) CO., LTD. (CN) 2025-09-23 — — US disclosed
US-11325902-B2 Benzenesulfonamide compounds and their use as therapeutic agents XENON PHARMACEUTICALS INC. (CA) 2022-05-10 — — US disclosed
US-20220135668-A1 Methods for Treating Psoriasis Using an Anti-IL-23 Antibody AMGEN INC. 2022-05-05 — — US disclosed
US-20220120754-A1 METHOD FOR SELECTING SUBJECT LIKELY BENEFITING FROM PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING CANCER SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2022-04-21 — — US disclosed
US-11299490-B2 Benzenesulfonamide compounds and their use as therapeutic agents XENON PHARMACEUTICALS INC. (CA) 2022-04-12 — — US disclosed
US-20220098600-A1 METHODS FOR THE IMPROVEMENT OF PRODUCT YIELD AND PRODUCTION IN A MICROORGANISM THROUGH THE ADDITION OF ALTERNATE ELECTRON ACCEPTORS DANSTAR FERMENT AG (CH) 2022-03-31 — — US disclosed
US-20220090045-A1 METHODS FOR PRODUCING ISOPROPANOL AND ACETONE IN A MICROORGANISM DANSTAR FERMENT AG (CH) 2022-03-24 — — US disclosed
US-20220081423-A1 THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF GENENTECH, INC. (US) 2022-03-17 — — US disclosed
CN-114097815-A Application of medical compound with amidine skeleton in resisting plant pathogenic bacteria 兰州大学 2022-03-01 — — CN disclosed
US-20220055977-A1 THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF GENENTECH, INC. (US) 2022-02-24 — — US disclosed
CN-114026079-A SGLT2/DPP4 inhibitor and application thereof 南京明德新药研发有限公司 2022-02-08 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346567-A1 SUBSTITUTED PYRIDINE AND PHENYL COMPOUNDS PAH, PC, MPC2 KMT2A 1935/4885RAB9A 2683/4885MAPT 1668/4885
US-20220081423-A1 THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF TRPV1, HCN4, TRPA1 KMT2A 1907/4885RAB9A 3448/4885MAPT 3785/4885
US-12421269-B2 SGLT2/DPP4 inhibitor and application thereof SLC5A2, SLC5A1, DPP4 KMT2A 1465/4885RAB9A 2742/4885MAPT 1787/4885
US-12467053-B2 Hybrid immunoglobulins with moving parts IGLV6-57, FCGRT, FCGR3B KMT2A 2337/4885RAB9A 2738/4885MAPT 2074/4885
US-11325902-B2 Benzenesulfonamide compounds and their use as therapeutic agents SCN1A, SCN1B, SCN2B KMT2A 2321/4885RAB9A 2453/4885MAPT 144/4885
US-11299490-B2 Benzenesulfonamide compounds and their use as therapeutic agents SCN1A, SCN1B, SCN2B KMT2A 2408/4885RAB9A 2532/4885MAPT 145/4885
US-20220055977-A1 THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF REN, RDX, MC2R KMT2A 1492/4885RAB9A 752/4885MAPT 3206/4885
US-20220120754-A1 METHOD FOR SELECTING SUBJECT LIKELY BENEFITING FROM PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING CANCER BCOR, TP53, BCL6 KMT2A 2204/4885RAB9A 3419/4885MAPT 2782/4885
US-20260001874-A1 DIHYDROQUINAZOLINONES EXHIBITING IMPROVED PROTECTIVE ACTIVITY AGAINST INTRACELLULARLY ACTING TOXINS AND INTRACELLULAR VIRUSES AND BACTERIA NSF, VAMP7, RAB7A KMT2A 4685/4885RAB9A 55/4885MAPT 2259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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