Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | PTAFR | P25105 | 6/20 | 0.33 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | EED | O75530 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12362300 | 0.62 | HDAC8 (0.37) | DNMT1RAD52UHRF1HDAC8HDAC4 | |
| SCHEMBL22716966 | 0.61 | CTSD (0.37) | — | |
| SCHEMBL7326935 | 0.60 | DNMT1 (0.51) | DNMT1RAD52UHRF1HDAC8HDAC4 | |
| SCHEMBL22716968 | 0.59 | NOS1 (0.40) | — | |
| SCHEMBL31167506 | 0.57 | HDAC8 (0.57) | HDAC8HDAC4PTAFRSMARCA2HDAC6 | |
| SCHEMBL21054186 | 0.56 | CA2 (0.31) | — | |
| SCHEMBL2493946 | 0.55 | DNMT1 (0.62) | DNMT1RAD52UHRF1HDAC8HDAC4 | |
| SCHEMBL6160294 | 0.54 | NOS3 (0.56) | — | |
| SCHEMBL27208844 | 0.54 | IDO1 (0.31) | — | |
| SCHEMBL1028400 | 0.53 | LGMN (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114126614-A | Heterocyclic compounds as PRMT5 inhibitors | 安杰斯制药公司 | 2022-03-01 | — | — | CN | claimed |
| CN-114126614-A | Heterocyclic compounds as PRMT5 inhibitors | 安杰斯制药公司 | 2022-03-01 | — | — | CN | disclosed |