SCHEMBL28715212

SCHEMBL28715212

C=CCC(=O)OB(O)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
GAA P10253 1/20 0.40
HTT P42858 2/20 0.37
CYP3A4 P08684 1/20 0.36
TSHR P16473 2/20 0.35
CYP2C19 P33261 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
PKM P14618 1/20 0.35
CA4 P22748 1/20 0.34
CA6 P23280 1/20 0.34
CA5A P35218 1/20 0.34
CA7 P43166 1/20 0.34
ENPP2 Q13822 1/20 0.34
CA14 Q9ULX7 1/20 0.34
CA5B Q9Y2D0 1/20 0.34
PCSK9 Q8NBP7 1/20 0.34
ORAI1 Q96D31 1/20 0.34
ORAI2 Q96SN7 1/20 0.34
ORAI3 Q9BRQ5 1/20 0.34
TRPV6 Q9H1D0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28532508 0.77 THRB (0.42) ALDH1A1CYP3A4TSHRCYP2C19SMN1; SMN2
SCHEMBL4508305 0.77 ELANE (0.42) ALDH1A1GAATSHRSMN1; SMN2CA4
SCHEMBL56273 0.74 ORAI1 (0.42) CYP3A4TSHRCYP2C19SMN1; SMN2PKM
SCHEMBL1672441 0.73 ORAI1 (0.46) ALDH1A1TSHRCA4CA6CA5A
SCHEMBL28664851 0.71 TRPV6 (0.44) ALDH1A1TSHRCA4CA6CA5A
SCHEMBL2143307 0.71 CYP3A4 (0.40) ALDH1A1CYP3A4TSHRSMN1; SMN2PKM
SCHEMBL163578 0.71 ALDH1A1 (0.50) ALDH1A1GAAHTTCYP3A4SMN1; SMN2
Phenylboronic Acid SCHEMBL28892104 0.70 CA4 (0.50) ALDH1A1HTTTSHRCYP2C19CA4
SCHEMBL20916961 0.70 LMNA (0.54) ALDH1A1GAATSHRSMN1; SMN2CA4
SCHEMBL651370 0.70 ORAI1 (0.42) ALDH1A1GAACYP3A4TSHRCA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114262340-A Preparation method of aminophenylboronic acid 蚌埠中实化学技术有限公司 2022-04-01 CN disclosed
CN-114262340-A Preparation method of aminophenylboronic acid 蚌埠中实化学技术有限公司 2022-04-01 CN disclosed