Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.38 |
| ▸ | ORAI2 | Q96SN7 | 3/20 | 0.38 |
| ▸ | ORAI3 | Q9BRQ5 | 3/20 | 0.38 |
| ▸ | TRPV6 | Q9H1D0 | 3/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | P4HB | P07237 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16987296 | 0.81 | THRB (0.40) | THRBAKT1ORAI1ORAI2ORAI3 | |
| SCHEMBL14334371 | 0.80 | ALDH1A1 (0.49) | THRBAKT1CA4CA7ENPP2 | |
| SCHEMBL56273 | 0.78 | ORAI1 (0.42) | THRBORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL1672441 | 0.77 | ORAI1 (0.46) | ORAI1ORAI2ORAI3TRPV6CA4 | |
| SCHEMBL28715212 | 0.77 | ALDH1A1 (0.40) | THRBAKT1ORAI1ORAI2ORAI3 | |
| SCHEMBL28664851 | 0.75 | TRPV6 (0.44) | ORAI1ORAI2ORAI3TRPV6CA4 | |
| SCHEMBL651370 | 0.74 | ORAI1 (0.42) | ORAI1ORAI2ORAI3TRPV6CA4 | |
| SCHEMBL20916961 | 0.74 | LMNA (0.54) | ORAI1ORAI2ORAI3TRPV6CA4 | |
| SCHEMBL384014 | 0.74 | ORAI1 (0.42) | ORAI1ORAI2ORAI3TRPV6CA4 | |
| SCHEMBL1789520 | 0.73 | PKM (0.42) | ORAI1ORAI2ORAI3TRPV6CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112533910-B | Monoethylenically unsaturated monomers and their use | 博斯蒂克股份公司 | 2024-05-10 | — | — | CN | claimed |
| CN-114748637-A | Phenylboronic acid modified nano-crystal drug stabilizing system and preparation method and application thereof | 中国药科大学 | 2022-07-15 | — | — | CN | claimed |
| CN-114712520-A | Nanocrystalline drug stabilizing system, preparation method, pharmaceutical composition and application | 中国药科大学 | 2022-07-08 | — | — | CN | claimed |
| CN-112533910-A | Monoethylenically unsaturated monomers and their use | 博斯蒂克股份公司 | 2021-03-19 | — | — | CN | claimed |
| CN-112533910-B | Monoethylenically unsaturated monomers and their use | 博斯蒂克股份公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-114712520-B | Nanocrystalline drug stabilization system, preparation method, pharmaceutical composition and application | 中国药科大学 | 2024-02-27 | — | — | CN | disclosed |
| CN-114748637-B | Phenylboronic acid modified nanocrystalline drug stabilization system and preparation method and application thereof | 中国药科大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-114748637-A | Phenylboronic acid modified nano-crystal drug stabilizing system and preparation method and application thereof | 中国药科大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-114712520-A | Nanocrystalline drug stabilizing system, preparation method, pharmaceutical composition and application | 中国药科大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-112533910-A | Monoethylenically unsaturated monomers and their use | 博斯蒂克股份公司 | 2021-03-19 | — | — | CN | disclosed |