SCHEMBL5379529

SCHEMBL5379529

CC(C)c1ccccc1-c1ccc(C2CCCCC2)c(C2CCCCC2)c1P

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.35
PTPRC P08575 1/20 0.35
PTPRF P10586 1/20 0.35
CDC25B P30305 1/20 0.35
PTGS2 P35354 1/20 0.35
DPP4 P27487 1/20 0.31
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
ADRA2A P08913 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
AXL P30530 1/20 0.30
TSHR P16473 2/20 0.30
HTT P42858 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL287733 0.82 S1PR1 (0.38) PTPN1PTPRCPTPRFCDC25BPTGS2
SCHEMBL161475 0.79 ROCK2 (0.43)
SCHEMBL28000625 0.79 ABCB1 (0.42) PTGS2
SCHEMBL788140 0.78 CAMKK2 (0.35) PTPN1PTPRCPTPRFCDC25BPTGS2
SCHEMBL68108 0.77 PTGS2 (0.39) PTGS2ALDH1A1LMNAL3MBTL1
SCHEMBL28152688 0.76 ROCK2 (0.38) PTGS2L3MBTL1
SCHEMBL11863751 0.76 HTR1A (0.40) PTGS2ADRA2AADRA2BADRA2CALDH1A1
SCHEMBL28152698 0.75 PTGS2 (0.39) PTGS2ALDH1A1LMNAL3MBTL1
SCHEMBL851115 0.74 HTR2C (0.34) PTGS2
SCHEMBL2725289 0.74 GABRA1 (0.41) PTPN1PTPRCPTPRFCDC25BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7268196-B2 Process for producing cycloolefin addition polymer JSR CORPORATION (JP) 2007-09-11 US disclosed
US-7241847-B2 Process for producing cycloolefin addition polymer JSR CORPORATION (JP) 2007-07-10 US disclosed
US-20070155922-A1 Process for producing cycloolefin addition polymer JSR CORPORATION (JP) 2007-07-05 US disclosed
US-20070123667-A1 PROCESS FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR CORPORATION (JP) 2007-05-31 US disclosed
EP-1712572-A1 PROCESS FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR Corporation (JP) 2006-10-18 EP disclosed
US-20060217505-A1 Process for producing cycloolefin addition polymer JRS CORPORATION (JP) 2006-09-28 US disclosed
EP-1657259-A1 PROCESS FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR Corporation (JP) 2006-05-17 EP disclosed