Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | FTO | Q9C0B1 | 10/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3282095 | 0.96 | HPGD (0.51) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL1986259 | 0.93 | HPGD (0.49) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL2989053 | 0.89 | HPGD (0.53) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL2407742 | 0.87 | HPGD (0.52) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL2225607 | 0.85 | HPGD (0.53) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL5711738 | 0.84 | HPGD (0.45) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL3468980 | 0.82 | HPGD (0.49) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL4802179 | 0.82 | HPGD (0.51) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL1991388 | 0.82 | FTO (0.42) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL8815694 | 0.80 | FTO (0.44) | HPGDALDH1A1ALOX12CYP2C9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1573068-B1 | HETEROCYCLIC FRET DYE CASSETTES FOR LABELING BIOLOGICAL MOLECULES AND THEIR USE IN DNA SEQUENCING | GE HEALTHCARE BIO SCIENCES (US) | 2010-10-20 | — | — | EP | disclosed |
| EP-1546391-A4 | ENERGY TRANSFER DYES, TERMINATORS AND USE THEREOF | AMERSHAM BIOSCIENCES CORP (US) | 2006-01-04 | — | — | EP | disclosed |
| EP-1546125-A4 | FLUORESCENT LABELING REAGENTS WITH MULTIPLE DONORS AND ACCEPTORS | AMERSHAM BIOSCIENCES CORP (US) | 2006-01-04 | — | — | EP | disclosed |
| EP-1573068-A4 | HETEROCYCLIC FRET DYE CASSETTES FOR LABELING BIOLOGICAL MOLECULES AND THEIR USE IN DNA SEQUENCING | AMERSHAM BIOSCIENCES CORP (US) | 2006-01-04 | — | — | EP | disclosed |
| US-20050260593-A1 | Fluorescent labeling reagents with multiple donors and acceptors | GE HEALTHCARE BIO-SCIENCES CORP. | 2005-11-24 | — | — | US | disclosed |
| US-20050255475-A1 | Energy transfer dyes, terminators and use thereof | GE HEALTHCARE BIO-SCIENCES CORP. | 2005-11-17 | — | — | US | disclosed |
| EP-1573068-A1 | HETEROCYCLIC FRET DYE CASSETTES FOR LABELING BIOLOGICAL MOLECULES AND THEIR USE IN DNA SEQUENCING | Amersham Biosciences Corp. (US) | 2005-09-14 | — | — | EP | disclosed |
| EP-1546125-A2 | FLUORESCENT LABELING REAGENTS WITH MULTIPLE DONORS AND ACCEPTORS | Amersham Biosciences Corp. (US) | 2005-06-29 | — | — | EP | disclosed |
| EP-1546391-A2 | ENERGY TRANSFER DYES, TERMINATORS AND USE THEREOF | Amersham Biosciences Corp. (US) | 2005-06-29 | — | — | EP | disclosed |
| US-6855503-B2 | Heterocyclic FRETdye cassettes for labeling biological molecules and their use in DNA sequencing | AMERSHAM BIOSCIENCES CORP (US) | 2005-02-15 | — | — | US | disclosed |
| WO-2004059011-A1 | HETEROCYCLIC FRET DYE CASSETTES FOR LABELING BIOLOGICAL MOLECULES AND THEIR USE IN DNA SEQUENCING | AMERSHAM BIOSCIENCES CORP (US) | 2004-07-15 | — | — | WO | disclosed |
| US-20040126763-A1 | Heterocyclic FRETdye cassettes for labeling biological molecules and their use in DNA sequencing | GE HEALTHCARE BIO-SCIENCES CORP. | 2004-07-01 | — | — | US | disclosed |
| WO-2004029578-A2 | ENERGY TRANSFER DYES, TERMINATORS AND USE THEREOF | AMERSHAM BIOSCIENCES CORP (US) | 2004-04-08 | — | — | WO | disclosed |
| WO-2004029579-A2 | FLUORESCENT LABELING REAGENTS WITH MULTIPLE DONORS AND ACCEPTORS | AMERSHAM BIOSCIENCES CORP (US) | 2004-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050255475-A1 | Energy transfer dyes, terminators and use thereof | DNTT, RNGTT, POLRMT | HPGD 2741/4885ALDH1A1 3197/4885ALOX12 4498/4885 |
| US-20040126763-A1 | Heterocyclic FRETdye cassettes for labeling biological molecules and their use in DNA sequencing | DNTT, POLL, POLRMT | HPGD 1094/4885ALDH1A1 2573/4885ALOX12 4364/4885 |
| US-20050260593-A1 | Fluorescent labeling reagents with multiple donors and acceptors | GFPT1, PFAS, HLCS | HPGD 2781/4885ALDH1A1 108/4885ALOX12 3468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.