Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PBK | Q96KB5 | 4/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287365 | 0.87 | NPY5R (0.41) | ALDH1A1HPGDPBKCACNA2D1ERCC5 | |
| SCHEMBL287774 | 0.85 | USP30 (0.36) | ALDH1A1HPGDPBKCACNA2D1ERCC5 | |
| SCHEMBL284518 | 0.84 | ALDH1A1 (0.34) | ALDH1A1NPC1RAB9AMEN1LMNA | |
| SCHEMBL287097 | 0.78 | MMP1 (0.38) | ALDH1A1POLBRENSMN1; SMN2 | |
| SCHEMBL287108 | 0.76 | RAB9A (0.39) | ALDH1A1HPGDCYP1A2TAS1R3NPC1 | |
| SCHEMBL287593 | 0.76 | ALDH1A1 (0.35) | ALDH1A1HPGDERCC5FEN1CYP1A2 | |
| SCHEMBL4160439 | 0.71 | TSHR (0.46) | ALDH1A1HPGDPBKCACNA2D1CYP1A2 | |
| SCHEMBL286982 | 0.71 | KMT2A (0.41) | ALDH1A1CYP1A2NPC1RAB9AMEN1 | |
| SCHEMBL287292 | 0.70 | ALDH1A1 (0.34) | ALDH1A1HPGDERCC5FEN1CYP1A2 | |
| SCHEMBL287829 | 0.69 | PBK (0.40) | ALDH1A1HPGDPBKCACNA2D1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | claimed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | claimed |