Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBK | Q96KB5 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287775 | 0.84 | GAA (0.36) | PBKSMN1; SMN2NPY5RMEN1KMT2A | |
| SCHEMBL284519 | 0.84 | ALOX15 (0.34) | SMN1; SMN2MEN1KMT2ATNKSTNKS2 | |
| SCHEMBL4160439 | 0.72 | TSHR (0.46) | PBKSMN1; SMN2MEN1KMT2AHSD17B10 | |
| SCHEMBL286983 | 0.70 | ALDH1A1 (0.40) | MEN1KMT2ATSHRALDH1A1CYP3A4 | |
| SCHEMBL287828 | 0.69 | ALDH1A1 (0.38) | PBKSMN1; SMN2MEN1KMT2AHSD17B10 | |
| SCHEMBL1279112 | 0.64 | RAB9A (0.69) | PBKMEN1KMT2AHSD17B10TSHR | |
| SCHEMBL1279114 | 0.64 | RAB9A (0.69) | PBKMEN1KMT2AHSD17B10TSHR | |
| SCHEMBL4152061 | 0.64 | ALDH1A1 (0.46) | SMN1; SMN2MEN1KMT2AHSD17B10LMNA | |
| SCHEMBL30803944 | 0.64 | SLC6A1 (0.52) | SMN1; SMN2KMT2ATNKSTNKS2LMNA | |
| SCHEMBL20460586 | 0.62 | SLC6A1 (0.53) | SMN1; SMN2KMT2ATNKSTNKS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | claimed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | claimed |