Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.38 |
| ▸ | MMP9 | P14780 | 3/20 | 0.38 |
| ▸ | MMP13 | P45452 | 3/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287259 | 0.87 | KMT2A (0.40) | MMP1MMP9MMP13ALDH1A1MAPT | |
| SCHEMBL287828 | 0.78 | ALDH1A1 (0.38) | RENALDH1A1SMN1; SMN2POLB | |
| SCHEMBL284518 | 0.78 | ALDH1A1 (0.34) | RENALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL286982 | 0.74 | KMT2A (0.41) | RENALDH1A1POLBMAPT | |
| SCHEMBL287108 | 0.74 | RAB9A (0.39) | ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL11798075 | 0.73 | NPC1 (0.59) | ALDH1A1SMN1; SMN2POLBHSD11B1 | |
| SCHEMBL4960293 | 0.68 | TRPM8 (0.50) | RENALDH1A1CDK9CAMK2A | |
| SCHEMBL2446469 | 0.67 | ALOX15 (0.59) | ALOX15POLB | |
| SCHEMBL288036 | 0.67 | POLB (0.39) | MMP1ALDH1A1ALOX15POLBHSD11B1 | |
| SCHEMBL2447403 | 0.67 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | claimed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | claimed |
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | disclosed |