Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | REN | P00797 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KHK | P50053 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287829 | 0.70 | PBK (0.40) | ALDH1A1KMT2AMEN1TSHRCYP3A4 | |
| SCHEMBL284519 | 0.70 | ALOX15 (0.34) | ALDH1A1KMT2AMEN1F10TSHR | |
| SCHEMBL9811504 | 0.69 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1CYP3A4CYP2D6 | |
| SCHEMBL286982 | 0.68 | KMT2A (0.41) | ALDH1A1KMT2ARENMEN1TSHR | |
| SCHEMBL25269242 | 0.68 | SLC6A1 (0.46) | ALDH1A1KMT2AF10TSHRKHK | |
| SCHEMBL2448229 | 0.67 | ULK1 (0.56) | ALDH1A1KHKCYP2C19 | |
| SCHEMBL7001156 | 0.65 | KMT2A (0.64) | KMT2AMEN1TSHRCYP2D6 | |
| SCHEMBL638646 | 0.65 | SLC6A1 (0.56) | KMT2ATSHRCYP2D6 | |
| SCHEMBL29541474 | 0.65 | RECQL (0.72) | ALDH1A1 | |
| SCHEMBL2450367 | 0.65 | HTR2C (0.56) | ALDH1A1TSHRCYP3A4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | claimed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | claimed |
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | disclosed |