Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287829 | 0.84 | PBK (0.40) | ALDH1A1HPGDRAB9AMAPTPBK | |
| SCHEMBL286983 | 0.75 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2A | |
| SCHEMBL287774 | 0.72 | USP30 (0.36) | ALDH1A1HPGDMAPTPBKUSP30 | |
| SCHEMBL284519 | 0.69 | ALOX15 (0.34) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4160439 | 0.66 | TSHR (0.46) | GAAALDH1A1HPGDRAB9AMAPT | |
| SCHEMBL24016844 | 0.61 | RXFP1 (0.59) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL287828 | 0.61 | ALDH1A1 (0.38) | ALDH1A1HPGDRAB9APBKSMN1; SMN2 | |
| SCHEMBL10797948 | 0.61 | ALDH1A1 (0.45) | GAAALDH1A1LMNA | |
| SCHEMBL2447500 | 0.60 | SSTR4 (0.59) | MAPTSMN1; SMN2KMT2ALMNA | |
| SCHEMBL12062195 | 0.60 | KMT2A (0.56) | ALDH1A1HPGDHTTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | claimed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | claimed |
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | disclosed |