SCHEMBL2878615

SCHEMBL2878615

CCOSCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.44
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
PRMT1 Q99873 1/20 0.39
IDO1 P14902 3/20 0.39
LTA4H P09960 2/20 0.39
NOS3 P29474 1/20 0.39
NOS1 P29475 1/20 0.39
NOS2 P35228 1/20 0.39
EGFR P00533 1/20 0.39
SLC6A4 P31645 1/20 0.38
POLB P06746 1/20 0.38
HSD17B10 Q99714 1/20 0.38
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TSHR P16473 1/20 0.37
MAOB P27338 1/20 0.37
NR2E3 Q9Y5X4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18970059 0.90 TAAR1 (0.44) TP53IDO1NPC1RAB9ASMN1; SMN2
SCHEMBL7314820 0.77 IDO1 (0.39) CYP1A2CYP3A4CYP2D6PRMT1IDO1
SCHEMBL10666358 0.77 IDO1 (0.39) CYP1A2CYP3A4CYP2D6PRMT1IDO1
SCHEMBL546541 0.76 CYP1A2 (0.42) TP53CYP1A2CYP3A4CYP2D6PRMT1
SCHEMBL8450 0.75 IDO1 (0.44) TP53CYP1A2CYP3A4CYP2D6PRMT1
SCHEMBL28860882 0.75 ALDH1A1 (0.42) TP53CYP3A4SMN1; SMN2TSHR
Water SCHEMBL28337532 0.73 IDO1 (0.43) TP53CYP1A2CYP3A4CYP2D6PRMT1
Dibenzyl Disulfide SCHEMBL27735307 0.73 TP53 (0.44) TP53CYP1A2CYP3A4CYP2D6PRMT1
Water SCHEMBL16321628 0.72 SCN1A (0.43)
SCHEMBL27533175 0.72 PAM (0.48) IDO1NOS3NOS1NOS2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108722677-B A kind of O- alkyl-S- hydroxyalkyl xanthate collecting agent and its preparation and application 中南大学 2019-06-07 CN disclosed
CN-108722677-A A kind of O- alkyl-S- hydroxyalkyl xanthate collecting agents and its preparation and application 中南大学 2018-11-02 CN disclosed
CN-108569989-A A method of preparing thiourethane co-production 2 mercapto ethanol or O- alkylthio group ethyl xanthates 中南大学 2018-09-25 CN disclosed
US-8754252-B2 Asymmetric cyclization processes using unsaturated nitro compounds NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2014-06-17 US disclosed
US-20130096338-A1 ASYMMETRIC CYCLIZATION PROCESSES USING UNSATURATED NITRO COMPOUNDS NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2013-04-18 US disclosed
US-20130004455-A1 POLY(ORGANOPHOSPHAZENE) COMPOSITION FOR BIOMATERIALS KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2013-01-03 US disclosed
US-8313771-B2 Phosphazene hydrogels with chemical corss-link, preparation method thereof and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2012-11-20 US disclosed
US-20100298576-A1 ASYMMETRIC CYCLIZATION PROCESSES USING UNSATURATED NITRO COMPOUNDS NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2010-11-25 US disclosed
US-20100297155-A1 PHOSPHAZENE HYDROGELS WITH CHEMICAL CORSS-LINK, PREPARATION METHOD THEREOF AND USE THEREOF DECA ITALIA S.R.L. (IT) 2010-11-25 US disclosed
US-4728646-A ANTITHROMBOTICS DR. KARL THOMAE GMBH (DE) 1988-03-01 US disclosed
US-4518596-A Antithrombotic use of 2-(perhydro-1,4-diazino)-pyrimido (5,4,D)-pyrimidines DR. KARL THOMAE GMBH (DE) 1985-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130004455-A1 POLY(ORGANOPHOSPHAZENE) COMPOSITION FOR BIOMATERIALS PHOSPHO1, PGLS, PHYKPL TP53 765/4885CYP1A2 1942/4885CYP3A4 1110/4885
US-20130096338-A1 ASYMMETRIC CYCLIZATION PROCESSES USING UNSATURATED NITRO COMPOUNDS NQO1, COASY, NOS2 TP53 3235/4885CYP1A2 130/4885CYP3A4 127/4885
US-20100297155-A1 PHOSPHAZENE HYDROGELS WITH CHEMICAL CORSS-LINK, PREPARATION METHOD THEREOF AND USE THEREOF PRUNE1, PHYKPL, PAPSS1 TP53 445/4885CYP1A2 1121/4885CYP3A4 619/4885
US-20100298576-A1 ASYMMETRIC CYCLIZATION PROCESSES USING UNSATURATED NITRO COMPOUNDS NQO1, COASY, NOS2 TP53 3235/4885CYP1A2 130/4885CYP3A4 127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.