Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 5/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1189491 | 0.85 | GSK3B (0.53) | F2RKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL846394 | 0.84 | KMT2A (0.58) | KMT2APOLBMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL14132732 | 0.81 | RXRA (0.47) | KMT2AMEN1KDM4E | |
| SCHEMBL1190059 | 0.81 | LMNA (0.44) | F2RKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL22435058 | 0.79 | KMT2A (0.42) | F2RKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL19862477 | 0.77 | KMT2A (0.47) | KMT2APOLBMEN1SMN1; SMN2NPC1 | |
| SCHEMBL16951122 | 0.77 | ALDH1A1 (0.39) | F2RKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL19107523 | 0.76 | CES2 (0.42) | PPARAPPARGSMN1; SMN2ALDH1A1 | |
| SCHEMBL27915406 | 0.76 | DDR1 (0.46) | F2RKMT2APOLBMEN1SMN1; SMN2 | |
| SCHEMBL16955483 | 0.75 | ABCB11 (0.36) | F2RKMT2AMEN1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101981035-A | Triazolium salts as PAR1 inhibitors, their preparation and their use as medicaments | SANOFI AVENTIS | 2011-02-23 | — | — | CN | disclosed |