SCHEMBL28797993

SCHEMBL28797993

OCCO[SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
RECQL P46063 1/20 0.46
GAA P10253 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
TSHR P16473 1/20 0.33
IDO1 P14902 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
PKM P14618 1/20 0.31
KCNA3 P22001 1/20 0.31
LTA4H P09960 1/20 0.30
KCNH3 Q9ULD8 1/20 0.30
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23701036 0.79 TDP1 (0.37) ALDH1A1TDP1TSHRKCNA3SMN1; SMN2
SCHEMBL28833848 0.77 ALDH1A1 (0.37) ALDH1A1KCNA3
SCHEMBL3481818 0.77 LMNA (0.39) ALDH1A1GAAMEN1KMT2AKCNA3
SCHEMBL23701154 0.77 KCNA3 (0.31) KCNA3
SCHEMBL31229726 0.76 CA2 (0.41) ALDH1A1GAATDP1TSHRMEN1
SCHEMBL4454040 0.76 CA1 (0.42) ALDH1A1TDP1IDO1SMN1; SMN2
SCHEMBL5382089 0.74 KCNA3 (0.54) ALDH1A1RECQLPKMKCNA3LTA4H
SCHEMBL864473 0.74 LTA4H (0.47) ALDH1A1TDP1TSHRLTA4H
SCHEMBL28871210 0.74 ALDH1A1 (0.34) ALDH1A1KCNA3
SCHEMBL28012385 0.73 TDP1 (0.48) ALDH1A1GAATDP1TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114787221-A Process for preparing thermoplastic polyurethanes having low enthalpy of fusion 科思创知识产权两合公司 2022-07-22 CN disclosed
CN-114761455-A Process for preparing thermoplastic polyurethanes having a low color number 科思创知识产权两合公司 2022-07-15 CN disclosed