SCHEMBL23701036

SCHEMBL23701036

BrCCO[SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 2/20 0.35
TRPA1 O75762 1/20 0.35
TSHR P16473 1/20 0.35
NPC1 O15118 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
KCNA3 P22001 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3481818 0.79 LMNA (0.39) ALDH1A1SMN1; SMN2KCNA3
SCHEMBL28833848 0.79 ALDH1A1 (0.37) ALDH1A1KCNA3
SCHEMBL28797993 0.79 ALDH1A1 (0.46) TDP1ALDH1A1TSHRSMN1; SMN2KCNA3
SCHEMBL23701154 0.79 KCNA3 (0.31) KCNA3
SCHEMBL4454040 0.77 CA1 (0.42) TDP1ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL31229726 0.77 CA2 (0.41) TDP1ALDH1A1TSHRMAPT
SCHEMBL864473 0.76 LTA4H (0.47) TDP1ALDH1A1TSHR
SCHEMBL5382089 0.76 KCNA3 (0.54) ALDH1A1MAPTRAB9AKCNA3
SCHEMBL28871210 0.76 ALDH1A1 (0.34) ALDH1A1KCNA3
SCHEMBL708400 0.74 RIPK1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807758-B2 Siloxane polymer and method of producing siloxane polymer JNC CORPORATION (JP) 2023-11-07 US disclosed
US-20210238419-A1 SILOXANE POLYMER AND METHOD OF PRODUCING SILOXANE POLYMER JNC CORPORATION (JP) 2021-08-05 US disclosed