Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27525176 | 0.80 | NOS2 (0.40) | NOS2 | |
| SCHEMBL28787513 | 0.78 | ROCK1 (0.37) | NOS2 | |
| SCHEMBL28858540 | 0.75 | NOS2 (0.36) | NOS2 | |
| SCHEMBL27972554 | 0.75 | ROCK2 (0.41) | NOS2 | |
| SCHEMBL28047241 | 0.75 | NOS2 (0.33) | NOS2 | |
| SCHEMBL28816888 | 0.75 | CTSK (0.36) | NOS2 | |
| SCHEMBL27530352 | 0.75 | NOS2 (0.37) | NOS2 | |
| SCHEMBL27808924 | 0.74 | ROCK2 (0.36) | NOS2 | |
| SCHEMBL28868753 | 0.73 | LDHA (0.41) | NOS2 | |
| SCHEMBL28313701 | 0.73 | NOS2 (0.40) | NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101821267-B | Compounds for the treatment of hepatitis c | BRISTOL MYERS SQUIBB CO | 2013-07-10 | — | — | CN | disclosed |