Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819258 | 0.92 | CYP1A1 (0.45) | GPR183L3MBTL1HDAC1LMNASMN1; SMN2 | |
| SCHEMBL28819245 | 0.88 | LMNA (0.52) | GPR183L3MBTL1HDAC1LMNASMN1; SMN2 | |
| SCHEMBL28819241 | 0.88 | LMNA (0.48) | GPR183L3MBTL1HDAC1LMNASMN1; SMN2 | |
| SCHEMBL28819261 | 0.84 | GPR183 (0.52) | GPR183L3MBTL1LMNASMN1; SMN2MAPT | |
| SCHEMBL28819248 | 0.83 | ALDH1A1 (0.43) | GPR183HDAC1LMNASMN1; SMN2MAPT | |
| SCHEMBL28819227 | 0.80 | L3MBTL1 (0.55) | GPR183L3MBTL1HDAC1LMNASMN1; SMN2 | |
| SCHEMBL28819260 | 0.76 | PKM (0.53) | GPR183LMNAMAPTMEN1KMT2A | |
| SCHEMBL28819247 | 0.71 | LMNA (0.54) | GPR183LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL28819242 | 0.71 | LMNA (0.58) | GPR183HDAC1LMNASMN1; SMN2MAPT | |
| SCHEMBL28838366 | 0.68 | MAPT (0.67) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634465-A | Sulfonyl piperazine-containing pentadiene ketone derivative and preparation method and application thereof | 贵州大学 | 2022-06-17 | — | — | CN | disclosed |