SCHEMBL28838403

SCHEMBL28838403

C[n+]1c(N)cc[nH]c1=O.NC(CCn1c(=O)cc[nH]c1=O)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 1/20 0.37
GRM2 Q14416 1/20 0.37
GRM8 O00222 1/20 0.34
GRM4 Q14833 1/20 0.34
GRIA1 P42261 4/20 0.33
GRIK1 P39086 1/20 0.33
GRIA2 P42262 3/20 0.32
GRIA4 P48058 3/20 0.32
GRIA3 P42263 2/20 0.32
ARG1 P05089 1/20 0.31
GRIK5 Q16478 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL154274 0.86 GRM5 (0.47) GRM5GRM2GRM8GRM4GRIA1
SCHEMBL5282402 0.72 GRIA1 (0.51) GRM5GRIA1GRIK1GRIA2GRIA4
SCHEMBL9694567 0.72 ALDH1A1 (0.33)
SCHEMBL4348692 0.67 ADRA1D (0.37)
D-Glutamate SCHEMBL28865803 0.64 GRM8 (0.51) GRM5GRM2GRM8GRM4GRIA1
SCHEMBL2930015 0.64 HASPIN (0.35)
SCHEMBL9118472 0.64 KDM4E (0.39)
SCHEMBL2983409 0.64 ADRA1D (0.34)
SCHEMBL17371774 0.64 FABP4 (0.50)
Lysine SCHEMBL2323422 0.64 GSR (0.44) GRM5GRM2GRM8GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115038790-A Synthesis of 3' -RNA oligonucleotides 阿尔尼拉姆医药品有限公司 2022-09-09 CN disclosed