Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28145817 | 0.86 | FAAH (0.37) | POLBSMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL28145809 | 0.85 | SIGMAR1 (0.56) | SIGMAR1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL28145787 | 0.83 | ALDH1A1 (0.54) | MEN1KMT2ALMNATSHRHTT | |
| SCHEMBL16826185 | 0.80 | GAA (0.39) | SIGMAR1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL28145793 | 0.77 | GALR3 (0.40) | SIGMAR1POLBHTTALDH1A1HTR1A | |
| SCHEMBL28145812 | 0.76 | KDM4E (0.58) | MEN1KMT2AACHEBACE1HTR1A | |
| SCHEMBL28145836 | 0.76 | PRMT6 (0.47) | MEN1KMT2ALMNATSHRHTT | |
| SCHEMBL28145820 | 0.76 | LMNA (0.51) | MEN1KMT2ALMNATSHRHTT | |
| SCHEMBL28144823 | 0.75 | OPRK1 (0.43) | MEN1KMT2ALMNAALDH1A1DCTPP1 | |
| SCHEMBL28144854 | 0.74 | HRH3 (0.47) | MEN1KMT2ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106659715-A | substituted aminotriazoles and methods of use thereof | 药物发现研究所 | 2017-05-10 | — | — | CN | claimed |
| CN-106659715-A | substituted aminotriazoles and methods of use thereof | 药物发现研究所 | 2017-05-10 | — | — | CN | disclosed |