SCHEMBL28850264

SCHEMBL28850264

O=C(O)c1cccc(C(F)(F)C(F)CF)c1C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS2R14 Q9NYV8 3/20 0.37
FABP4 P15090 1/20 0.36
ALDH1A1 P00352 4/20 0.34
ALOX15 P16050 3/20 0.34
LMNA P02545 2/20 0.34
ALB P02768 1/20 0.34
KCNK3 O14649 1/20 0.33
KCNK9 Q9NPC2 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
FOLH1 Q04609 1/20 0.33
MAPT P10636 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
DHODH Q02127 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33
AKR1C3 P42330 1/20 0.33
MRGPRX4 Q96LA9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28488953 0.77 SORT1 (0.32)
SCHEMBL9013418 0.77 ALDH1A1 (0.44) TAS2R14FABP4ALDH1A1ALOX15LMNA
SCHEMBL2964734 0.77 TAS2R14 (0.51) TAS2R14FABP4ALDH1A1ALOX15LMNA
SCHEMBL27075282 0.75 TAS2R14 (0.50) TAS2R14FABP4ALDH1A1ALOX15LMNA
SCHEMBL7095723 0.75 ALOX15 (0.43) TAS2R14FABP4ALDH1A1ALOX15LMNA
SCHEMBL3822237 0.75 ALOX15 (0.42) TAS2R14FABP4ALDH1A1ALOX15LMNA
SCHEMBL4960164 0.75 ALDH1A1 (0.41) TAS2R14FABP4ALDH1A1ALOX15LMNA
SCHEMBL29404866 0.74 TAS2R14 (0.42) TAS2R14FABP4ALDH1A1ALOX15LMNA
SCHEMBL145576 0.74 TAS2R14 (0.42) TAS2R14FABP4ALDH1A1ALOX15LMNA
SCHEMBL30269555 0.74 TAS2R14 (0.42) TAS2R14FABP4ALDH1A1ALOX15LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115141370-A Polyimide, metal-clad laminate, and circuit board 日铁化学材料株式会社 2022-10-04 CN disclosed
CN-115141560-A Adhesive layer, circuit board using the same, and strip line 日铁化学材料株式会社 2022-10-04 CN disclosed