Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3511229 | 0.72 | CYP2C19 (0.40) | PKMALDH1A1SLC40A1NAMPT | |
| SCHEMBL20679918 | 0.71 | NAMPT (0.46) | ALDH1A1SLC40A1NAMPTNPC1SMN1; SMN2 | |
| SCHEMBL28291561 | 0.70 | SLC40A1 (0.50) | PKMALDH1A1SLC40A1NAMPTSMN1; SMN2 | |
| SCHEMBL5785411 | 0.69 | LTA4H (0.38) | PKMALDH1A1NPC1RAB9ACDK5 | |
| SCHEMBL8797268 | 0.69 | FBP1 (0.38) | PKMALDH1A1SLC40A1NAMPTSMN1; SMN2 | |
| SCHEMBL14636694 | 0.69 | ALDH1A1 (0.53) | PKMALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25429553 | 0.68 | CA2 (0.39) | — | |
| SCHEMBL27500441 | 0.68 | — | — | |
| SCHEMBL3545877 | 0.68 | — | — | |
| SCHEMBL20679889 | 0.67 | CYP2A6 (0.41) | ALDH1A1SLC40A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8754234-B2 | Chiral 2-(benzylsulfinyl)thiazole derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]thiazole derivatives, processes for their preparation and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2014-06-17 | — | — | US | disclosed |
| US-20100285958-A1 | Chiral 2-(benzylsulfinyl)Thiazole derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]thiazole derivatives, processes for their preparation and their use as herbicides and plant growth regulators | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100285958-A1 | Chiral 2-(benzylsulfinyl)Thiazole derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]thiazole derivatives, processes for their preparation and their use as herbicides and plant growth regulators | STS, SULT2A1, SLTM | PKM 382/4885ALDH1A1 933/4885SLC40A1 3951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.