Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 2/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | F9 | P00740 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10052153 | 0.81 | TLR8 (0.42) | LIMK1ENPP1RETFLT1KDR | |
| SCHEMBL1806582 | 0.76 | ALDH1A1 (0.56) | LIMK1RETFLT1KDRMAPK14 | |
| SCHEMBL28215029 | 0.74 | APP (0.45) | LIMK1ENPP1RETFLT1KDR | |
| SCHEMBL9307538 | 0.72 | LIPG (0.37) | LIMK1ENPP1RETFLT1KDR | |
| SCHEMBL8092634 | 0.72 | ALDH1A1 (0.51) | LIMK1ENPP1RETFLT1KDR | |
| SCHEMBL16004771 | 0.72 | RET (0.47) | LIMK1ENPP1RETFLT1KDR | |
| SCHEMBL900791 | 0.72 | ALOX5 (0.43) | LIMK1ENPP1RETFLT1KDR | |
| SCHEMBL28819175 | 0.72 | RET (0.41) | LIMK1ENPP1RETFLT1KDR | |
| SCHEMBL1772204 | 0.72 | RET (0.41) | LIMK1ENPP1RETFLT1KDR | |
| SCHEMBL27845716 | 0.72 | RET (0.41) | LIMK1ENPP1RETFLT1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214471-B | The preparation method of compound with Na-dependent glucose transporter inhibitory activity | 田边三菱制药株式会社 | 2018-02-06 | — | — | CN | disclosed |