Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | CTSG | P08311 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | BID | P55957 | 3/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2416249 | 0.78 | LIPG (0.44) | NR1H2NR1H3LIPGALOX5PTGS2 | |
| SCHEMBL8070862 | 0.78 | ALOX15 (0.46) | LIPGALOX15HSD17B10ALOX5PTGS2 | |
| SCHEMBL29508750 | 0.77 | LIPG (0.46) | NR1H2NR1H3LIPGGPR3ELANE | |
| SCHEMBL28975089 | 0.77 | LIPG (0.46) | NR1H2NR1H3LIPGGPR3ELANE | |
| SCHEMBL9162757 | 0.73 | DRD2 (0.44) | NR1H2NR1H3LIPGELANECTSG | |
| SCHEMBL28390492 | 0.71 | LIPG (0.53) | NR1H2NR1H3LIPGGPR3ALOX5 | |
| SCHEMBL20612831 | 0.69 | ALOX15 (0.44) | CA12CA9ALOX15HSD17B10ALOX5 | |
| SCHEMBL1024526 | 0.69 | LIPG (0.59) | NR1H2NR1H3LIPGGPR3ALOX5 | |
| SCHEMBL5823386 | 0.69 | PNMT (0.58) | NR1H2NR1H3LIPGALOX5PTGS2 | |
| SCHEMBL11296054 | 0.68 | DHFR (0.47) | NR1H2NR1H3LIPGGPR3ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107778241-A | A kind of new synthetic method of the dihydrophenanthridine class compound of 6 aryl 5,6 | 中山大学 | 2018-03-09 | — | — | CN | disclosed |