Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | EPM2A | O95278 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.32 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.32 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6333359 | 0.75 | TRPA1 (0.34) | MAOAMAOBKCNA3KCNA5IDO1 | |
| SCHEMBL16432225 | 0.74 | CYP3A4 (0.35) | MAOAMAOBKCNA3ALDH1A1CYP3A4 | |
| SCHEMBL20839528 | 0.71 | CYP3A4 (0.34) | MAOAKCNA3KCNA5ALDH1A1CYP3A4 | |
| SCHEMBL5987116 | 0.70 | XDH (0.46) | MAOBCASP3IDO1EPM2APTPRC | |
| SCHEMBL28216629 | 0.70 | ALDH1A1 (0.36) | MAOAMAOBIDO1EPM2APTPRC | |
| SCHEMBL28730278 | 0.69 | KIF11 (0.33) | NOTUMEPHX2 | |
| SCHEMBL30395860 | 0.69 | MAOA (0.62) | MAOAMAOBKCNA3KCNA5CYP3A4 | |
| SCHEMBL16345419 | 0.69 | CYP1A1 (0.39) | — | |
| SCHEMBL17708944 | 0.69 | MAOA (0.62) | MAOAMAOBKCNA3KCNA5CYP3A4 | |
| SCHEMBL29144468 | 0.67 | FTO (0.41) | MAOAMAOBKCNA3KCNA5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440515-A | Substituted benzofuranyl and benzoxazole based compound and application thereof | 卡尔约药物治疗公司 | 2018-08-24 | — | — | CN | disclosed |
| CN-105492437-B | Substituted benzofuranyl and benzoxazolyl compounds and uses thereof | 卡尔约药物治疗公司 | 2018-05-11 | — | — | CN | disclosed |