Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22194925 | 0.85 | CA12 (0.40) | CA12CA1CA7CA14ATM | |
| SCHEMBL19403533 | 0.85 | CA12 (0.40) | CA12CA1CA7CA14ATM | |
| SCHEMBL28628216 | 0.83 | ALDH1A1 (0.49) | CA12CA7CA14KMT2AAKT1 | |
| SCHEMBL28859014 | 0.79 | MTNR1A (0.36) | CA12CA1CA7CA14L3MBTL1 | |
| SCHEMBL9325266 | 0.77 | KEAP1 (0.50) | ATMTDP1ALDH1A1 | |
| SCHEMBL1380801 | 0.76 | TDP1 (0.61) | L3MBTL1KMT2ATDP1ALDH1A1 | |
| SCHEMBL17045901 | 0.73 | LMNA (0.46) | CA12CA7CA14AKT1CA9 | |
| SCHEMBL12040169 | 0.73 | DGAT1 (0.34) | — | |
| SCHEMBL10578604 | 0.73 | HDAC1 (0.56) | L3MBTL1KMT2ATDP1ALDH1A1 | |
| SCHEMBL9070581 | 0.73 | DGAT1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181051-B | Preparation method of sulfoxide compound containing indole skeleton | 扬州大学 | 2024-02-20 | — | — | CN | disclosed |
| CN-115181051-A | Preparation method of sulfoxide compound containing indole skeleton | 扬州大学 | 2022-10-14 | — | — | CN | disclosed |