Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.46 |
| ▸ | CA2 | P00918 | 7/20 | 0.46 |
| ▸ | CA5A | P35218 | 6/20 | 0.46 |
| ▸ | CA7 | P43166 | 6/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28030573 | 0.77 | CA2 (0.49) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL28225354 | 0.73 | L3MBTL1 (0.61) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL1874184 | 0.69 | CYP2C9 (0.42) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL14028112 | 0.66 | CA2 (0.57) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL5679972 | 0.65 | CISD1 (0.37) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL10869347 | 0.65 | CA1 (0.43) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL14028113 | 0.65 | CA2 (0.53) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL3665121 | 0.65 | CA2 (0.47) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL20899645 | 0.64 | MEN1 (0.65) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL28954610 | 0.63 | CA2 (0.37) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008322-B | sulfonamide derivatives as BC L-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases | ABBVIE 公司 | 2018-09-04 | — | — | CN | disclosed |